CECR2 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the Cat Eye Syndrome Chromosome Region, Candidate 2 (CECR2) protein, also known as Adenosine Deaminase-like Protein 2 (ADAL2). CECR2 is a member of the adenosine deaminase (ADA) enzyme family and is involved in the modification of nucleosides. Specifically, CECR2 plays a role in the deamination of adenosine to inosine in RNA, a process known as RNA editing. RNA editing is a post-transcriptional modification that can impact gene expression and protein function. Inhibitors of CECR2 are developed primarily for research purposes, serving as essential tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this enzyme in the context of RNA editing and nucleoside modification.
CECR2 inhibitors are typically composed of small molecules or chemical compounds specifically designed to interfere with the enzymatic activity of CECR2. By inhibiting CECR2, these compounds can potentially disrupt the deamination of adenosine to inosine in RNA, leading to alterations in RNA sequences and potentially affecting gene expression and protein function. Researchers use CECR2 inhibitors in laboratory settings to manipulate the activity of this enzyme and study its roles in various cellular processes, particularly those related to RNA editing and nucleoside modification. These inhibitors provide valuable insights into the molecular mechanisms by which CECR2 influences RNA editing and contribute to a deeper understanding of its significance in the context of cellular biology and gene regulation. While CECR2 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of CECR2-mediated RNA editing.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Incorporates into DNA and RNA, causing demethylation and potentially reducing CECR2 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor that can induce gene hypomethylation, potentially lowering CECR2 levels. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Selective HDAC inhibitor that could alter gene expression, potentially impacting CECR2 transcription. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
HDAC inhibitor that alters chromatin conformation, which might reduce expression of the CECR2 gene. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
A potent HDAC inhibitor that could affect histone acetylation and CECR2 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid and HDAC inhibitor, could influence CECR2 gene transcription. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $214.00 $247.00 $1463.00 | 2 | |
HDAC inhibitor, which may modify chromatin and alter the expression of the CECR2 gene. | ||||||
Chidamide | 743420-02-2 | sc-364462 sc-364462A sc-364462B | 1 mg 5 mg 25 mg | $62.00 $250.00 $1196.00 | ||
HDAC inhibitor that may impact transcriptional regulation, potentially affecting CECR2 expression. | ||||||
CI 994 | 112522-64-2 | sc-205245 sc-205245A | 10 mg 50 mg | $99.00 $536.00 | 1 | |
An HDAC inhibitor that could change epigenetic marks and possibly downregulate CECR2 gene expression. | ||||||