Date published: 2026-4-24

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CDKL5 Antibodies

Santa Cruz Biotechnology delivers a wide array of CDKL5 monoclonal antibodies for research in understanding CDKL5's role in various biological processes. CDKL5 monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CDKL5, or cyclin-dependent kinase-like 5, is a serine/threonine kinase that plays a crucial role in neuronal development and function. Mutations in the CDKL5 gene are associated with severe neurodevelopmental disorders, including CDKL5 deficiency disorder, which is characterized by early-onset seizures and developmental delays. Understanding CDKL5 function is essential for elucidating its involvement in synaptic regulation and potential therapeutic targets for related disorders. CDKL5 monoclonal antibodies enable precise detection and analysis of CDKL5 expression patterns in neural tissues. Researchers can investigate CDKL5's molecular interactions and signaling pathways using multiple experimental approaches. Advanced imaging techniques combined with CDKL5 monoclonal antibodies allow visualization of protein localization in cellular compartments. Santa Cruz Biotechnology monoclonal antibodies for CDKL5 support researchers worldwide in advancing our understanding of neurological development and potential therapeutic interventions.

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CDKL5 Antibodies

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CDKL5 Antibody (D-12)

sc-376314mouse IgG2b κ222-520 (h)WB, IP, IF, ELISAm, r, h
10
(4)

CDKL5 CRISPR Knockout, HDR and Double Nickase Plasmids

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CDKL5 CRISPR/Cas9 KO Plasmid (h)

sc-403409hGene KnockoutGFP
1
(0)

CDKL5 HDR Plasmid (h)

sc-403409-HDRhHomology Directed RepairPuromycin
1
(0)

CDKL5 Double Nickase Plasmid (h)

sc-403409-NIChGene KnockoutPuromycin
1
(0)

CDKL5 Double Nickase Plasmid (h2)

sc-403409-NIC-2hGene KnockoutPuromycin
1
(0)

CDKL5 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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CDKL5 siRNA (h)

sc-72849hGene SilencingN/A0
(0)

CDKL5 shRNA Plasmid (h)

sc-72849-SHhGene SilencingPuromycin0
(0)

CDKL5 shRNA (h) Lentiviral Particles

sc-72849-VhGene SilencingPuromycin0
(0)

CDKL5 siRNA (m)

sc-72850mGene SilencingN/A0
(0)

CDKL5 shRNA Plasmid (m)

sc-72850-SHmGene SilencingPuromycin0
(0)

CDKL5 shRNA (m) Lentiviral Particles

sc-72850-VmGene SilencingPuromycin0
(0)