Date published: 2026-4-24

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CD33 Antibodies

Santa Cruz Biotechnology features a diverse variety of CD33 monoclonal antibodies for research in understanding CD33's role in immune regulation. CD33 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CD33, also known as Siglec-3, is a sialic acid-binding immunoglobulin-like lectin that plays a crucial role in the regulation of immune responses, particularly in myeloid cells. CD33 is involved in the inhibition of immune cell activation and has been implicated in the pathogenesis of various hematological malignancies, making it a significant target for therapeutic interventions. Understanding CD33 function is essential for developing strategies to modulate immune responses in diseases such as acute myeloid leukemia (AML). Research utilizing CD33 monoclonal antibodies can reveal important mechanisms in cellular signaling pathways and immune system regulation. Investigating CD33's role in disease progression can lead to improved therapeutic approaches for various hematological conditions. CD33 expression patterns in different cell types provide valuable information about immune system development and function. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance our understanding of CD33's role in human health and disease.

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CD33 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CD33 Antibody (6C5/2)

sc-53199mouse IgG1 κ(h)WB, IP, FCMm, r, h
1
(4)

CD33 Antibody (B-3)

sc-514119mouse IgG1 κ18-107 (m)WB, IP, IF, ELISAm, r, h

new

(2)

CD33 Antibody (P67.6)

sc-19660mouse IgG1 κ(h)IF, FCMh
6
(4)

CD33 Antibody (B-9)

sc-374450mouse IgG2a κ231-340 (h)WB, IP, IF, ELISAh

new

(1)

CD33 Antibody (E-6)

sc-376184mouse IgG1 κ231-340 (h)WB, IP, IF, ELISAh

new

(2)

CD33 Antibody (CD33-4D3)

sc-59020mouse IgG2b κ(h)FCMh

new

(1)

CD33 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD33 CRISPR/Cas9 KO Plasmid (h)

sc-401011hGene KnockoutGFP0
(0)

CD33 HDR Plasmid (h)

sc-401011-HDRhHomology Directed RepairPuromycin0
(0)

CD33 Double Nickase Plasmid (h)

sc-401011-NIChGene KnockoutPuromycin0
(0)

CD33 Double Nickase Plasmid (h2)

sc-401011-NIC-2hGene KnockoutPuromycin0
(0)

CD33 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD33 CRISPR Activation Plasmid (h)

sc-401011-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD33 CRISPR Activation Plasmid (h2)

sc-401011-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD33 Lentiviral Activation Particles (h)

sc-401011-LAChGene ActivationPuro, Blast, Hygro0
(0)

CD33 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD33 siRNA (h)

sc-42782hGene SilencingN/A0
(0)

CD33 shRNA Plasmid (h)

sc-42782-SHhGene SilencingPuromycin0
(0)

CD33 shRNA (h) Lentiviral Particles

sc-42782-VhGene SilencingPuromycin0
(0)

CD33 siRNA (m)

sc-42783mGene SilencingN/A0
(0)

CD33 shRNA Plasmid (m)

sc-42783-SHmGene SilencingPuromycin0
(0)

CD33 shRNA (m) Lentiviral Particles

sc-42783-VmGene SilencingPuromycin0
(0)

CD33 Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

CD33 (h): 293T Lysate

sc-114798h0
(0)