Date published: 2026-5-6

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CCM Antibodies

Santa Cruz Biotechnology provides a broad selection of CCM Antibodies for studying CCM (Cerebral Cavernous Malformation) protein through various research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CCM protein maintains vascular integrity and regulates endothelial cell function in the body. Mutations in the CCM gene can lead to the formation of cavernous malformations in the brain and other organs, potentially causing serious neurological complications. Research has shown that CCM protein dysfunction may contribute to various vascular disorders and developmental abnormalities. Understanding CCM protein function and regulation provides insights into potential therapeutic approaches for vascular diseases. Current research focuses on identifying the molecular mechanisms through which CCM protein influences blood vessel development and maintenance. Investigating CCM protein interactions with other cellular components helps reveal its role in maintaining healthy vasculature. Ongoing studies continue to uncover new aspects of CCM protein's involvement in cellular signaling pathways and tissue development. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of CCM protein's role in vascular health and disease progression.

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CCM Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CCM3 Antibody (C-8)

sc-365586mouse IgG2b κ3-191 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(2)

CCM3 Antibody (F-12)

sc-365587mouse IgG2a κ3-191 (h)WB, IP, IF, ELISAm, r, h
3
(2)

CCM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CCM3 CRISPR/Cas9 KO Plasmid (h)

sc-403858hGene KnockoutGFP0
(0)

CCM3 HDR Plasmid (h)

sc-403858-HDRhHomology Directed RepairPuromycin0
(0)

Pdcd-10 CRISPR/Cas9 KO Plasmid (m)

sc-425154mGene KnockoutGFP0
(0)

Pdcd-10 HDR Plasmid (m)

sc-425154-HDRmHomology Directed RepairPuromycin0
(0)

CCM siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CCM3 siRNA (h)

sc-62084hGene SilencingN/A
3
(0)

CCM3 shRNA Plasmid (h)

sc-62084-SHhGene SilencingPuromycin
3
(0)

CCM3 shRNA (h) Lentiviral Particles

sc-62084-VhGene SilencingPuromycin
3
(0)

CCM3 siRNA (m)

sc-62085mGene SilencingN/A
1
(0)

CCM3 shRNA Plasmid (m)

sc-62085-SHmGene SilencingPuromycin
1
(0)

CCM3 shRNA (m) Lentiviral Particles

sc-62085-VmGene SilencingPuromycin
1
(0)