CCDC61 Inhibitors
The chemical class of CCDC61 inhibitors presents a range of compounds that directly or indirectly impact its functions in identical protein binding, microtubule binding, centriole assembly, and mitotic spindle assembly. Colchicine acts as a direct inhibitor by disrupting microtubule binding, impacting CCDC61's role in centriole assembly and mitotic spindle assembly. Paclitaxel, though indirect, stabilizes microtubules, affecting CCDC61's microtubule binding and influencing centriole assembly. Nocodazole, a direct inhibitor, depolymerizes microtubules, disrupting CCDC61's microtubule binding activity and impacting centriole assembly. Vinblastine indirectly inhibits CCDC61 by disrupting microtubule dynamics, influencing centriole assembly and mitotic spindle assembly. Griseofulvin acts as a direct inhibitor by inhibiting microtubule formation, affecting CCDC61's role in centriole assembly and mitotic spindle assembly. Colcemid indirectly inhibits CCDC61 by preventing microtubule polymerization, impacting its microtubule binding activity and influencing centriole assembly. Epothilone B directly promotes microtubule stabilization, disrupting CCDC61's microtubule binding and affecting centriole assembly. Podophyllotoxin, though indirect, disrupts microtubule dynamics, influencing CCDC61's microtubule binding and impacting centriole assembly.
Vinorelbine, a direct inhibitor, interferes with microtubule dynamics, disrupting CCDC61's role in centriole assembly and mitotic spindle assembly. Docetaxel acts indirectly by promoting microtubule stabilization, impacting CCDC61's microtubule binding and influencing centriole assembly. Vinflunine directly disrupts microtubule dynamics, affecting CCDC61's microtubule binding and influencing centriole assembly. Thiabendazole indirectly inhibits CCDC61 by interfering with microtubule polymerization, impacting its microtubule binding activity and influencing centriole assembly. These inhibitors collectively contribute to our understanding of CCDC61's intricate role in cellular processes and offer potential avenues for further research into its functions and implications in cellular organization and division. The chemical class of CCDC61 inhibitors provides a valuable framework for investigating the regulatory mechanisms associated with identical protein binding, microtubule binding, centriole assembly, and mitotic spindle assembly.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine serves as a direct inhibitor of CCDC61, disrupting its microtubule binding activity. By binding to tubulin, it interferes with microtubule formation, impacting CCDC61's role in mitotic spindle assembly and centriole assembly. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Taxol acts as an indirect inhibitor of CCDC61 by promoting microtubule stabilization. This disrupts the dynamic nature of microtubules, affecting CCDC61's microtubule binding activity and influencing centriole assembly and mitotic spindle assembly. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole functions as a direct inhibitor of CCDC61 by depolymerizing microtubules. Its interference with microtubule dynamics impacts CCDC61's microtubule binding activity, affecting centriole assembly and mitotic spindle assembly. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine serves as an indirect inhibitor of CCDC61 by disrupting microtubule dynamics. By binding tubulin, it interferes with microtubule polymerization, influencing CCDC61's microtubule binding activity and subsequently impacting centriole assembly and mitotic spindle assembly. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin acts as a direct inhibitor of CCDC61 by inhibiting microtubule formation. Its interference with tubulin polymerization disrupts CCDC61's microtubule binding activity, affecting centriole assembly and mitotic spindle assembly. | ||||||
Colcemid | 477-30-5 | sc-202550A sc-202550 sc-202550B sc-202550C sc-202550D sc-202550E | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg | $67.00 $159.00 $312.00 $928.00 $1856.00 $6706.00 | 7 | |
Colcemid functions as an indirect inhibitor of CCDC61 by preventing microtubule polymerization. Its interference with tubulin dynamics impacts CCDC61's microtubule binding activity, influencing centriole assembly and mitotic spindle assembly. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B acts as a direct inhibitor of CCDC61 by promoting microtubule stabilization. Its binding to tubulin disrupts microtubule dynamics, affecting CCDC61's microtubule binding activity and influencing centriole assembly and mitotic spindle assembly. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin serves as an indirect inhibitor of CCDC61 by disrupting microtubule dynamics. Its interference with tubulin polymerization impacts CCDC61's microtubule binding activity, affecting centriole assembly and mitotic spindle assembly. | ||||||
Vinorelbine base | 71486-22-1 | sc-205885 sc-205885A sc-205885B sc-205885C sc-205885D | 1 mg 5 mg 25 mg 100 mg 1 g | $28.00 $79.00 $255.00 $775.00 $1938.00 | ||
Vinorelbine functions as a direct inhibitor of CCDC61 by interfering with microtubule dynamics. Its binding to tubulin disrupts microtubule formation, impacting CCDC61's microtubule binding activity and influencing centriole assembly and mitotic spindle assembly. | ||||||
Docetaxel | 114977-28-5 | sc-201436 sc-201436A sc-201436B | 5 mg 25 mg 250 mg | $85.00 $325.00 $1072.00 | 16 | |
Docetaxel acts as an indirect inhibitor of CCDC61 by promoting microtubule stabilization. Its interference with tubulin dynamics disrupts CCDC61's microtubule binding activity, affecting centriole assembly and mitotic spindle assembly. | ||||||