cathepsin C Substrates

Santa Cruz Biotechnology now offers a broad range of cathepsin C Substrates for use in various applications. Cathepsin C substrates are essential tools in the study of cathepsin C, a lysosomal cysteine protease that plays a critical role in immune function, particularly in the activation of serine proteases in immune cells like neutrophils and cytotoxic T lymphocytes. Cathepsin C, also known as dipeptidyl peptidase I, is involved in the removal of dipeptides from the N-terminus of protein substrates, which is a crucial step in the maturation and activation of several proteases that are important for immune responses, including granzymes and cathepsins G and H. By utilizing cathepsin C substrates, researchers can specifically monitor the activity of this enzyme, providing insights into its functional role in both normal physiology and in the context of immune-related diseases. These substrates are widely used in research to understand the biochemical pathways regulated by cathepsin C, as well as in high-throughput screening assays aimed at identifying novel modulators of its activity. Understanding the activity of cathepsin C through these substrates is also significant in studies of diseases such as chronic inflammatory conditions, where dysregulation of this enzyme can lead to pathological outcomes. The use of cathepsin C substrates is thus crucial for advancing research in immunology, cell biology, and pathology, offering a deeper understanding of how proteolytic processing by cathepsin C influences cellular processes and immune functions. View detailed information on our available cathepsin C Substrates by clicking on the product name.