caspase-3 Activators
Santa Cruz Biotechnology now offers a broad range of caspase-3 Activators. Caspase family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-3 Activators offered by Santa Cruz activate caspase-3 and, in some cases, other apoptosis and tumor related proteins. View detailed caspase-3 Activator specifications, including caspase-3 Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
By inhibiting the proteasome, this drug disrupts protein homeostasis in the cell, causing endoplasmic reticulum stress and triggering caspase-3 activation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
It intercalates into DNA, disrupting RNA and DNA synthesis, leading to cellular stress and activation of the intrinsic apoptotic pathway, which activates caspase-3. | ||||||
Proscillaridin A | 466-06-8 | sc-500903A sc-500903B sc-500903 | 1 mg 5 mg 10 mg | $182.00 $494.00 $686.00 | 4 | |
Proscillaridin A acts as a selective modulator of caspase-3, characterized by its ability to induce conformational changes in the enzyme. Its unique structural features allow for specific interactions with the active site, enhancing substrate accessibility. The compound's distinct electrostatic properties influence the enzyme's stability and activity, while its kinetic profile reveals a nuanced regulation of apoptotic processes, contributing to the intricate balance of cellular signaling. | ||||||