Date published: 2026-5-5

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casein kinase II alpha Inhibitors

Santa Cruz Biotechnology now offers a broad range of casein kinase II alpha Inhibitors for use in various applications. Casein kinase II alpha (CK2α) inhibitors are powerful tools in the study of cellular processes regulated by this multifunctional serine/threonine protein kinase, which is involved in a wide array of cellular functions, including cell growth, proliferation, and survival. CK2α is known for its ability to phosphorylate a variety of substrates, making it a key player in numerous signaling pathways that maintain cellular homeostasis and regulate gene expression. By inhibiting CK2α, researchers can explore the specific roles this kinase plays in these critical biological processes, providing insights into how CK2α activity impacts cellular function. CK2α inhibitors are particularly valuable in research aimed at understanding the kinase's involvement in signal transduction pathways, where CK2α modulates the activity of other proteins and enzymes, influencing downstream effects on cellular metabolism and stress responses. These inhibitors are also employed in high-throughput screening assays to identify novel targets and pathways regulated by CK2α, broadening our understanding of the kinase's impact on cellular dynamics. The ability to selectively inhibit CK2α provides researchers with a precise tool to investigate the molecular mechanisms underlying various cellular functions, making CK2α inhibitors essential in both basic and applied biological research. The use of these inhibitors across different experimental models, from in vitro studies to more complex in vivo systems, has significantly contributed to the advancement of knowledge in fields such as molecular biology, biochemistry, and cell signaling. View detailed information on our available casein kinase II alpha Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

TBB

17374-26-4sc-202830
sc-202830A
sc-202830C
sc-202830B
sc-202830D
10 mg
25 mg
50 mg
100 mg
250 mg
$245.00
$370.00
$454.00
$760.00
$1817.00
17
(1)

TBB is a synthetic compound that inhibits CK2 activity by competing with ATP for binding to the CK2 ATP-binding site. This blocks CK2's catalytic function, leading to reduced phosphorylation of its substrates.

CX-4945

1009820-21-6sc-364475
sc-364475A
2 mg
50 mg
$183.00
$800.00
9
(2)

CX-4945 is a synthetic compound and a selective inhibitor of CK2. It binds to the ATP-binding site of CK2α, inhibiting its catalytic activity. This leads to the downregulation of CK2-dependent signaling pathways and cellular processes.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

Ellagic Acid is a natural compound that has been suggested to inhibit CK2 activity. Its specific mechanism of action on CK2α is not well-established.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

DRB is a synthetic compound that inhibits CK2 activity by competing with ATP for binding to the CK2 ATP-binding site. This blocks CK2's catalytic function, leading to reduced phosphorylation of its substrates.

TMCB

905105-89-7sc-361383
sc-361383A
10 mg
50 mg
$135.00
$557.00
(0)

TMCB is a synthetic compound that inhibits CK2 activity by competing with ATP for binding to the CK2 ATP-binding site. This blocks CK2's catalytic function, leading to reduced phosphorylation of its substrates.

Emodin

518-82-1sc-202601
sc-202601A
sc-202601B
50 mg
250 mg
15 g
$105.00
$214.00
$6255.00
2
(1)

Emodin is a natural compound that has been proposed to inhibit CK2 activity. Its specific mechanism of action on CK2α is not well-established.

Apigenin

520-36-5sc-3529
sc-3529A
sc-3529B
sc-3529C
sc-3529D
sc-3529E
sc-3529F
5 mg
100 mg
1 g
5 g
25 g
100 g
1 kg
$33.00
$214.00
$734.00
$1151.00
$2348.00
$3127.00
$5208.00
22
(1)

Apigenin is a natural compound that has been suggested to inhibit CK2 activity. Its specific mechanism of action on CK2α is not well-established.