Date published: 2026-4-24

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CaBP4 Activators

CaBP4 Activators represent a class of chemical compounds specifically tailored to modulate the activity or expression of CaBP4, or Calcium Binding Protein 4. This protein, as its name suggests, binds calcium and is intricately involved in calcium-dependent signaling processes within the cell. Located predominantly in retinal photoreceptors, CaBP4 plays a crucial role in fine-tuning calcium-mediated responses, ensuring that cellular activities related to vision are precisely coordinated. Calcium, being a ubiquitous secondary messenger, is vital in numerous cellular pathways, and proteins like CaBP4 contribute to the specificity and exactitude of these calcium-driven signals.

Compounds that can be categorized as CaBP4 Activators might employ a variety of mechanisms to influence this protein's function. Some could enhance the transcriptional or translational processes, leading to an elevated presence of CaBP4 in the cellular environment. Others might act by strengthening the affinity of CaBP4 for calcium, ensuring more robust and prolonged signaling events when calcium concentrations change. Yet another group might stabilize the CaBP4 protein structure, ensuring its sustained activity. Given the fundamental importance of calcium in cellular signaling and the specialized role of CaBP4 in the retina, understanding and modulating its activity has profound implications for cellular biology. Exploring the realm of CaBP4 Activators offers a gateway to better appreciate the complexities of calcium signaling, especially in specialized cells, and underscores the importance of precision in these signaling pathways.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

A calcium ionophore known to increase intracellular calcium levels.

Ryanodine

15662-33-6sc-201523
sc-201523A
1 mg
5 mg
$223.00
$799.00
19
(2)

Modulates ryanodine receptors, leading to changes in intracellular calcium levels.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Known to release intracellular calcium stores.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

It increases cAMP levels, which can indirectly influence calcium signaling.

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$28.00
$53.00
37
(1)

A modulator of IP3 receptors, potentially affecting intracellular calcium release.

EGTA

67-42-5sc-3593
sc-3593A
sc-3593B
sc-3593C
sc-3593D
1 g
10 g
100 g
250 g
1 kg
$21.00
$65.00
$120.00
$251.00
$815.00
23
(1)

A calcium chelating agent; while it binds and reduces free calcium, it might have indirect effects on calcium-binding proteins.

Dantrolene

7261-97-4sc-500165
25 mg
$350.00
7
(0)

Affects ryanodine receptors, influencing calcium release from the sarcoplasmic reticulum.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

Another calcium ionophore that allows calcium passage across cell membranes.

(±)-Bay K 8644

71145-03-4sc-203324
sc-203324A
sc-203324B
1 mg
5 mg
50 mg
$84.00
$196.00
$817.00
(0)

Enhances calcium channel activity, potentially increasing calcium levels intracellularly.