Date published: 2025-9-10

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C6orf48 Inhibitors

C6orf48 Inhibitors refers to a group of chemical compounds that inhibit the function of the protein encoded by the C6orf48 gene, also known as SNHG32 (Small Nucleolar RNA Host Gene 32). The C6orf48 protein has been associated with the process of translation initiation, elongation, or termination based on the information available 1. Given this association, it is plausible to infer that inhibitors targeting C6orf48 could potentially modulate these critical stages of translation, thereby affecting the gene expression process at the translational level. The translation process is central to how a cell interprets genetic information to produce functional proteins, and any modulation at this level could have broad implications on cellular function and phenotype. The precise mechanism through which C6orf48 Inhibitors might exert their inhibitory effect is not elucidated in the available literature. However, based on the general principle of inhibition, these compounds might interact with C6orf48 in a manner that reduces or abolishes its function in the translation process. Such interaction could potentially be achieved by binding to the active or binding sites of the C6orf48 protein, thereby inhibitng its normal interaction with other molecular entities involved in translation. Through such inhibitory actions, C6orf48 Inhibitors could serve as effective modulators of translation, offering a means to alter gene expression profiles at the translational level. Without detailed information on the chemical structure and properties of these inhibitors, the extent and specificity of their inhibitory actions remain an open area of investigation.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Interacts with DNA by intercalation, inhibiting RNA polymerase and thus halting transcription. Consequently, it can reduce the transcriptional activity of genes.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

A potent inhibitor of RNA polymerase II. By binding to the enzyme, it blocks mRNA elongation, which can lead to reduced synthesis of mRNA.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Targets the 60S ribosomal subunit, inhibiting peptide bond formation and thus preventing translational elongation.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A nucleoside analog that incorporates into DNA and inhibits DNA methyltransferases, leading to hypomethylation. It can modulate transcriptional regulation.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

Inhibits inosine-5'-monophosphate dehydrogenase, affecting guanine nucleotide synthesis, potentially affecting transcription processes.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

Directly inhibits the phosphorylation of RNA polymerase II, attenuating transcriptional elongation.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Binds to the 60S ribosomal subunit, affecting peptide bond formation and inhibiting protein synthesis.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Interferes with DNA topoisomerase I function, potentially affecting transcription.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$38.00
$58.00
$102.00
$202.00
8
(1)

Binds to HSP90, affecting maturation and stability of many proteins, indirectly modulating protein levels.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Inhibits cyclin-dependent kinases, potentially affecting transcriptional progression.