C20orf79 Inhibitors

SCP2 sterol binding domain containing 1 (SCP2D1) is a protein that is characterized by its ability to bind sterol molecules. As part of the sterol carrier protein family, SCP2D1 plays a role in the intracellular transport of lipids, particularly sterols and other hydrophobic molecules. The transport of these molecules is critical for various biological processes, including membrane biogenesis, lipid metabolism, and the synthesis of steroid hormones.SCP2D1 contains a domain that is homologous to the sterol carrier protein 2 (SCP2), which is known for its role in the shuttling of cholesterol and other lipids between cellular membranes. The sterol-binding domain of SCP2D1 facilitates the transfer of sterols across the aqueous environment of the cytoplasm, thereby influencing the distribution and homeostasis of sterols within the cell.

The protein is essential for maintaining the balance of cholesterol and other sterols within cells, which is vital for cell membrane integrity and function. Abnormal levels of cholesterol and sterols can lead to a variety of diseases, including atherosclerosis and other cardiovascular diseases. SCP2D1 may also be involved in the metabolism of fatty acids and the activation of peroxisome proliferator-activated receptors (PPARs), which are nuclear receptors that play a significant role in lipid metabolism and energy homeostasis.