Key pathways that could be relevant to C20orf173's function include the PI3K/Akt/mTOR pathway, the MAPK/ERK pathway, and the ubiquitin-proteasome system. Rapamycin and LY294002, by inhibiting mTOR and PI3K respectively, can affect cell growth and survival pathways. U0126 and PD98059, targeting MEK in the MAPK/ERK pathway, are involved in cell differentiation and proliferation, potentially intersecting with C20orf173-related processes.
Inhibitors like Bortezomib and MG132 target the proteasome, affecting protein turnover and degradation, which can influence a range of cellular signaling pathways. DAPT, as a γ-secretase inhibitor, affects Notch signaling, a pathway significant in cell fate decisions and differentiation.These inhibitors represent a broad spectrum of cellular targets and processes, offering potential indirect means to influence the activity of C20orf173
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor, impacting cell growth, proliferation, and survival pathways that could intersect with C20orf173 function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, targeting key signaling pathways involved in cell survival and proliferation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a selective inhibitor of MEK1/2, part of the MAPK/ERK pathway, potentially influencing pathways related to C20orf173. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 specifically inhibits MEK in the MAPK/ERK pathway, which is involved in cellular differentiation and proliferation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, affecting inflammatory response and stress-related pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, impacting apoptosis, inflammation, and cellular differentiation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor, affecting multiple signaling pathways and protein degradation processes. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 inhibits the proteasome, leading to accumulation of proteins and affecting cell cycle and apoptosis. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
DAPT is a γ-secretase inhibitor, impacting Notch signaling, which is important in cell differentiation and fate decisions. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3K), which are involved in various cellular processes. | ||||||