Date published: 2025-9-14

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C20orf132 Activators

Maestro Heat-Like Repeat Family Member 8 (MROH8) is a protein encoded by the MROH8 gene in humans. Although the full range of functions of MROH8 is not entirely understood, it belongs to a family of proteins characterized by the presence of maestro heat-like repeats (MROH). These repeat motifs are thought to be involved in protein-protein interactions, which are crucial for various cellular processes.MROH8 is expressed in several tissues, with a higher expression profile in the brain and testes, suggesting a potential role in the neurological system and reproductive function. The precise cellular functions of MROH8 remain to be fully elucidated; however, proteins with similar MROH domains have been implicated in the regulation of signal transduction pathways, vesicle trafficking, and membrane dynamics.

Structurally, MROH8 contains multiple tandem repeats that are typical of the MROH family, which may facilitate complex formation with other proteins. These interactions can potentially influence intracellular signaling cascades and impact the regulation of cellular growth, differentiation, and apoptosis.Due to its expression pattern and structural features, MROH8 is hypothesized to participate in critical developmental processes and could be especially important in the context of neuronal development and spermatogenesis. Genetic studies have hinted at the importance of MROH8, with mutations or disruptions in the MROH8 gene potentially linked to developmental disorders or diseases; however, direct associations and functional consequences are not yet clearly defined.

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