Akna Domain Containing 1" is a protein that, as suggested by its name, contains an AKNA domain, which is a region typically involved in cellular processes such as cell proliferation, differentiation, and possibly gene regulation. The AKNA domain is characterized by its role in mediating protein-protein interactions, and proteins harboring this domain may function as transcription factors or be involved in the organization of chromatin structure, thereby influencing gene expression patterns.The exact functions of "Akna Domain Containing 1" in humans are not fully elucidated, but proteins with similar domains have been implicated in the regulation of developmental processes. For instance, proteins with AKNA domains have been shown to play roles in neurogenesis, the immune response, and cell cycle regulation. They may participate in the assembly of protein complexes that are crucial for transcriptional control during cell differentiation and during the response to various cellular signals.
Given the involvement of AKNA domain-containing proteins in the immune system, "Akna Domain Containing 1" could be implicated in the regulation of lymphocyte proliferation or in the formation of immune synapses, which are essential for the activation and function of immune cells. The AKNA domain can facilitate interactions with other regulatory proteins, possibly affecting the transcription of genes that are critical for immune responses.Furthermore, this protein could have a role in maintaining cellular homeostasis by regulating apoptosis or cell survival pathways. The disruption or altered expression of "Akna Domain Containing 1" might lead to developmental abnormalities or contribute to the pathogenesis of diseases where cell proliferation and differentiation are dysregulated, such as cancer.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that inhibits calcineurin, Cyclosporine can modulate T-cell activation, potentially influencing pathways or processes associated with AKNAD1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, Rapamycin suppresses cell growth and proliferation, potentially affecting cellular processes that AKNAD1 is involved in. | ||||||
NFκB Activation Inhibitor II, JSH-23 | 749886-87-1 | sc-222061 sc-222061C sc-222061A sc-222061B | 5 mg 10 mg 50 mg 100 mg | $210.00 $252.00 $1740.00 $1964.00 | 34 | |
An NF-κB inhibitor, JSH-23 may impact gene expression related to immune response and cytokinesis, potentially influencing AKNAD1's functional context. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, SB203580 could alter stress response pathways and cytokine production, indirectly affecting processes regulated by AKNAD1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, LY294002 may affect various signaling pathways involved in cell survival, proliferation, and immune responses, potentially impacting AKNAD1's role. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor, U0126 blocks the MAPK/ERK pathway, possibly influencing cellular differentiation and immune responses, indirectly affecting AKNAD1's functionality. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor, SP600125 could modulate transcription factors and cytokine production, potentially impacting the cellular processes associated with AKNAD1. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $153.00 | 5 | |
A Bruton's tyrosine kinase (BTK) inhibitor, Ibrutinib may affect B-cell receptor signaling, indirectly influencing pathways related to AKNAD1's activity. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
An NF-κB inhibitor, BAY 11-7082 may affect transcription of genes involved in immune responses and cell division, indirectly influencing AKNAD1. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
By inhibiting TNF-α and modulating immune responses, Thalidomide could indirectly affect cellular processes and pathways associated with AKNAD1. | ||||||