C17orf87 Inhibitors

C17orf87 inhibitors like LY294002 and Wortmannin target PI3K, a lipid kinase involved in signaling pathways that regulate a multitude of cellular processes including growth, proliferation, and survival. By inhibiting PI3K, these compounds disrupt the PI3K/AKT pathway, which can have downstream effects on proteins that are part of or regulated by this pathway, potentially including C17orf87. Rapamycin, by inhibiting mTOR, affects a central regulator of cell growth and metabolism, which can have cascading effects on proteins regulated by these fundamental processes.

Other compounds such as SB203580 and SP600125 inhibit MAP kinase pathways, which are involved in responding to stress signals and inflammation. The inhibition of these pathways can alter the cellular response to stress and therefore the function of proteins associated with these pathways, which may include C17orf87. ZM-447439's inhibition of Aurora kinases affects cell division, which is a process where C17orf87 may play a role, although this role is not directly established. KN-93 inhibits CaMKII, which is involved in calcium signaling pathways that affect numerous cellular processes including memory formation in neurons, and could possibly intersect with signaling pathways involving C17orf87.