Date published: 2026-1-26

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BTC Activators

BTC Activators are a specialized class of chemical compounds designed to modulate the activity of betacellulin (BTC), a member of the epidermal growth factor (EGF) family of proteins. BTC is a polypeptide growth factor that plays a crucial role in regulating cellular proliferation, differentiation, and survival by binding to its receptor, the EGF receptor (EGFR). EGFR activation triggers a cascade of intracellular signaling pathways, influencing various cellular processes, including development, tissue repair, and maintenance of normal physiological functions. BTC, specifically, is notable for its ability to activate EGFR and initiate downstream signaling events.

BTC Activators are compounds engineered to interact with BTC and modify its binding affinity or its ability to activate EGFR. These activators can either enhance or inhibit BTC's effects, depending on their chemical structure and mode of action. By targeting BTC, these compounds provide researchers with a tool to investigate the intricacies of BTC-EGFR signaling, helping to elucidate the precise mechanisms by which this growth factor regulates cellular responses. The study of BTC Activators is essential for advancing our understanding of the molecular pathways associated with EGFR activation and its involvement in various biological processes. Researchers continue to explore the mechanisms of BTC activation and its implications in cellular physiology, offering insights into the complex network of growth factor signaling pathways and their roles in tissue development and homeostasis.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tyrphostin AG 1478

175178-82-2sc-200613
sc-200613A
5 mg
25 mg
$96.00
$421.00
16
(1)

A tyrosine kinase inhibitor specific for EGFR. It can affect BTC activity indirectly by modulating EGFR downstream signaling.

Erlotinib, Free Base

183321-74-6sc-396113
sc-396113A
sc-396113B
sc-396113C
sc-396113D
500 mg
1 g
5 g
10 g
100 g
$87.00
$135.00
$293.00
$505.00
$3827.00
42
(0)

Another EGFR inhibitor, it can modulate BTC signaling indirectly by targeting the EGFR pathway.

Pelitinib

257933-82-7sc-208155
5 mg
$430.00
(0)

An irreversible EGFR inhibitor, influencing BTC activity indirectly through the EGFR pathway.

Canertinib

267243-28-7sc-207397
10 mg
$260.00
3
(0)

An irreversible pan-ErbB inhibitor, which can affect BTC signaling by targeting multiple ErbB receptors.

Afatinib

439081-18-2sc-364398
sc-364398A
5 mg
10 mg
$114.00
$198.00
13
(2)

A potent irreversible EGFR family inhibitor, it can indirectly influence BTC activity by altering EGFR/ErbB4 signaling.

Neratinib

698387-09-6sc-364549
sc-364549A
sc-364549B
sc-364549C
sc-364549D
5 mg
25 mg
100 mg
500 mg
1 g
$92.00
$214.00
$383.00
$755.00
$1250.00
4
(1)

An irreversible inhibitor of EGFR, HER2, and ErbB4, impacting BTC activity by modulating these pathways.

TAK 165

366017-09-6sc-361372
sc-361372A
10 mg
50 mg
$139.00
$781.00
(0)

An inhibitor of HER2/ErbB2, with potential indirect effects on BTC signaling via the ErbB pathway.