BPIL2 inhibitors are a class of chemical compounds designed to target and inhibit the function of the BPIL2 protein, a member of the BPI fold-containing (BPIF) family. BPIL2, also known as Bactericidal/Permeability-Increasing Fold-Containing Family Member L2, is believed to play a role in immune response regulation, specifically in the defense mechanisms against pathogens. The BPIF family is characterized by proteins that possess structural features involved in binding to microbial components and modulating immune responses. BPIL2 inhibitors are developed to study the specific functions of this protein in immune processes, potentially affecting its interactions with other proteins or microbial elements.
BPIL2 inhibitors are typically small molecules that are designed to fit into the active or binding sites of the BPIL2 protein, effectively blocking its activity. These inhibitors can disrupt the normal signaling or immune-modulatory functions that BPIL2 is involved in by preventing it from binding to its natural ligands or interacting with other cellular components. The chemical composition of BPIL2 inhibitors may vary, but they often include specific moieties that enable selective binding and inhibition. By using BPIL2 inhibitors, researchers can investigate the precise biological roles of this protein in immune-related pathways and its influence on cellular signaling. These inhibitors serve as crucial tools for understanding the molecular mechanisms behind BPIL2's role in host defense and immune system regulation, shedding light on the intricate interactions between this protein and other components in the immune network.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This compound inhibits histone deacetylase (HDAC), potentially reducing BPIL2 expression by increasing chromatin condensation, thereby limiting transcriptional access. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
By inhibiting DNA methyltransferase, this chemical may lead to hypomethylation of DNA, which could decrease BPIL2 gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
It intercalates into DNA, inhibiting RNA polymerase and potentially decreasing BPIL2 transcription. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
This compound inhibits RNA polymerase II, potentially reducing BPIL2 mRNA synthesis. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
This compound inhibits eukaryotic protein synthesis, potentially reducing BPIL2 protein levels indirectly. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
As an mTOR inhibitor, it could downregulate protein synthesis, including that of BPIL2. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
It binds to DNA, potentially blocking transcription factor binding required for BPIL2 expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
This compound raises endosomal pH, which could interfere with transcription factor activity related to BPIL2 expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
It may inhibit the transcription of various genes, potentially including BPIL2. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
It inhibits cyclin-dependent kinases, potentially leading to reduced transcription of BPIL2. | ||||||