Date published: 2026-2-14

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BPIL2 Inhibitors

BPIL2 inhibitors are a class of chemical compounds designed to target and inhibit the function of the BPIL2 protein, a member of the BPI fold-containing (BPIF) family. BPIL2, also known as Bactericidal/Permeability-Increasing Fold-Containing Family Member L2, is believed to play a role in immune response regulation, specifically in the defense mechanisms against pathogens. The BPIF family is characterized by proteins that possess structural features involved in binding to microbial components and modulating immune responses. BPIL2 inhibitors are developed to study the specific functions of this protein in immune processes, potentially affecting its interactions with other proteins or microbial elements.

BPIL2 inhibitors are typically small molecules that are designed to fit into the active or binding sites of the BPIL2 protein, effectively blocking its activity. These inhibitors can disrupt the normal signaling or immune-modulatory functions that BPIL2 is involved in by preventing it from binding to its natural ligands or interacting with other cellular components. The chemical composition of BPIL2 inhibitors may vary, but they often include specific moieties that enable selective binding and inhibition. By using BPIL2 inhibitors, researchers can investigate the precise biological roles of this protein in immune-related pathways and its influence on cellular signaling. These inhibitors serve as crucial tools for understanding the molecular mechanisms behind BPIL2's role in host defense and immune system regulation, shedding light on the intricate interactions between this protein and other components in the immune network.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

This compound inhibits histone deacetylase (HDAC), potentially reducing BPIL2 expression by increasing chromatin condensation, thereby limiting transcriptional access.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

By inhibiting DNA methyltransferase, this chemical may lead to hypomethylation of DNA, which could decrease BPIL2 gene expression.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

It intercalates into DNA, inhibiting RNA polymerase and potentially decreasing BPIL2 transcription.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

This compound inhibits RNA polymerase II, potentially reducing BPIL2 mRNA synthesis.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

This compound inhibits eukaryotic protein synthesis, potentially reducing BPIL2 protein levels indirectly.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

As an mTOR inhibitor, it could downregulate protein synthesis, including that of BPIL2.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

It binds to DNA, potentially blocking transcription factor binding required for BPIL2 expression.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

This compound raises endosomal pH, which could interfere with transcription factor activity related to BPIL2 expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

It may inhibit the transcription of various genes, potentially including BPIL2.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$259.00
41
(3)

It inhibits cyclin-dependent kinases, potentially leading to reduced transcription of BPIL2.