Biotin Derivatives

N-[23-(9-Mercaptononyl)-3,6,9,12,15,18,21-Heptaoxatricosanyl]-N'-(biotinyl)ethylenediamine is a biotin derivative featuring a unique heptaoxatricosanyl chain that enhances solubility and stability in aqueous environments. The mercaptononyl group introduces thiol reactivity, allowing for selective conjugation to various biomolecules. This compound's design promotes specific interactions with avidin or streptavidin, facilitating robust binding in diverse biochemical contexts.

KAPA (hydrochloride) is a biotin derivative characterized by its unique structural features that enhance its reactivity and binding affinity. The presence of a flexible linker facilitates conformational adaptability, allowing for efficient interactions with target proteins. Its distinct functional groups promote specific molecular recognition, enabling selective binding to avidin and streptavidin. This compound exhibits favorable kinetics in conjugation reactions, making it a versatile tool in biochemical applications.

Biotin-PEG3400-MTS-CAE is a biotin derivative distinguished by its polyethylene glycol (PEG) moiety, which enhances solubility and biocompatibility. The MTS (maleimide-thiol) functionality allows for selective and stable conjugation to thiol-containing biomolecules, promoting efficient cross-linking. Its unique structure facilitates enhanced molecular interactions, leading to improved stability and reactivity in various biochemical environments, making it an effective agent for targeted applications.

N-Biotinyl-6-amino-2-naphthoic Acid is a biotin derivative characterized by its naphthoic acid core, which introduces unique aromatic interactions that enhance binding affinity to biotin receptors. The amino group facilitates hydrogen bonding, promoting specific molecular recognition. Its distinct structure allows for versatile reactivity in coupling reactions, enabling the formation of stable conjugates. This compound's unique properties contribute to its behavior in diverse biochemical pathways.

[Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(2-aminoethanoic Acid) is a biotin derivative distinguished by its dithiomethylene moiety, which introduces unique redox properties and enhances nucleophilic reactivity. The presence of multiple amino groups facilitates complexation with metal ions, promoting intricate molecular interactions. This compound exhibits distinctive solubility characteristics, influencing its behavior in various biochemical environments and reaction kinetics, making it a versatile participant in synthetic pathways.

2-[N2-(N6-t-Boc-6-aminocaproyl)-N6-(6-biotinamidocaproy)-L-lysinylamido]ethyl Methanethiosulfonate is a biotin derivative characterized by its methanethiosulfonate group, which enables selective thiol modifications. This compound exhibits unique reactivity through disulfide bond formation, facilitating targeted conjugation in biochemical systems. Its structural complexity allows for diverse interactions with biomolecules, influencing stability and solubility in various environments, thus enhancing its utility in molecular biology applications.

Biotin-deca(ethylene glycol)-disulphide is a biotin derivative distinguished by its elongated ethylene glycol chain, which enhances solubility and flexibility in aqueous environments. This compound features a disulfide linkage that enables reversible thiol modifications, promoting specific interactions with proteins and other biomolecules. Its unique structure facilitates efficient conjugation and enhances the stability of biotinylated constructs, making it a versatile tool for probing molecular interactions in complex biological systems.

Fmoc-D-Lys(Biotin)-OH is a biotin derivative characterized by its Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which allows for selective deprotection during peptide synthesis. This compound exhibits strong affinity for avidin and streptavidin, facilitating robust biotin-protein interactions. The presence of the lysine residue enhances solubility and reactivity, enabling efficient conjugation to various biomolecules. Its unique structure supports diverse applications in bioconjugation and molecular labeling.

NHS-SS-(+)-Biotin is a biotin derivative featuring a N-hydroxysuccinimide (NHS) moiety, which enhances its reactivity towards amines, facilitating efficient conjugation. This compound exhibits a unique ability to form stable amide bonds, promoting specific molecular interactions. Its distinct disulfide linkage allows for controlled release in redox environments, making it suitable for applications requiring precise modulation of biotinylation. The compound's solubility and stability further support diverse biochemical applications.

Bio-Lys(bioinamidocaproyl)ethyl-MTS, a biotin derivative, showcases remarkable reactivity through its MTS (maleimide-thiol) functionality, enabling selective conjugation with thiol-containing biomolecules. This compound facilitates efficient biotinylation via a unique Michael addition mechanism, promoting stable thioether linkages. Its hydrophilic nature enhances solubility in aqueous environments, while its structural flexibility allows for diverse interactions, making it a versatile tool in biochemical research.