Molecular structure of KAPA (hydrochloride), CAS Number: 177408-65-0
KAPA (hydrochloride) (CAS 177408-65-0)
Alternate Names:
7-keto-8-Aminopelargomic Acid
Application:
KAPA (hydrochloride) is an intermediate in biotin biosynthesis
CAS Number:
177408-65-0
Molecular Weight:
223.7
Molecular Formula:
C9H17NO3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
KAPA (hydrochloride) is an intermediate in the biotin biosynthetic pathway. It is a synthetic prescursor of biotin, which plays a role in many reactions to the survival of many organisms. It is a crystalline solid at room temperature. It is soluble in organic solvents such as ethanol and DMSO.
KAPA (hydrochloride) (CAS 177408-65-0) References
- The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis. | Lin, S. and Cronan, JE. 2012. J Biol Chem. 287: 37010-20. PMID: 22965231
- Pimelic acid, the first precursor of the Bacillus subtilis biotin synthesis pathway, exists as the free acid and is assembled by fatty acid synthesis. | Manandhar, M. and Cronan, JE. 2017. Mol Microbiol. 104: 595-607. PMID: 28196402
- Discovery of the Biosynthetic Machinery for Stravidins, Biotin Antimetabolites. | Montaser, R. and Kelleher, NL. 2020. ACS Chem Biol. 15: 1134-1140. PMID: 31887014
- α-proteobacteria synthesize biotin precursor pimeloyl-ACP using BioZ 3-ketoacyl-ACP synthase and lysine catabolism. | Hu, Y. and Cronan, JE. 2020. Nat Commun. 11: 5598. PMID: 33154364
Substrate of:
Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KAPA (hydrochloride), 1 mg | sc-221787 | 1 mg | $39.00 | |||
KAPA (hydrochloride), 5 mg | sc-221787A | 5 mg | $122.00 |