Date published: 2025-12-18

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β lactamase Inhibitors

Santa Cruz Biotechnology now offers a broad range of beta lactamase Inhibitors for use in various applications. Beta lactamase inhibitors are crucial chemical tools in scientific research, particularly in the study of bacterial resistance mechanisms. Beta lactamase enzymes are produced by certain bacteria to break down beta-lactam antibiotics, such as penicillins and cephalosporins, rendering them ineffective. By inhibiting these enzymes, researchers can investigate the mechanisms behind antibiotic resistance, a growing concern in both clinical and environmental settings. Beta lactamase inhibitors allow scientists to explore how bacteria evolve to counteract the effects of antibiotics and to identify potential strategies to overcome this resistance. These inhibitors are invaluable in microbiology and biochemistry research, where they are used to study the structure and function of beta lactamase enzymes, as well as to screen for new inhibitors that could enhance the efficacy of existing antibiotics. Additionally, beta lactamase inhibitors are employed in genetic studies to understand how resistance genes are transferred between bacterial populations, providing insights into the spread of antibiotic resistance. The availability of a diverse range of beta lactamase inhibitors enables researchers to design experiments that are tailored to specific bacterial strains and resistance mechanisms, advancing our understanding of bacterial biology and contributing to the development of novel antimicrobial strategies. View detailed information on our available beta lactamase Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sulbactam

68373-14-8sc-272516
1 g
$80.00
(0)

Sulbactam acts as a potent beta-lactamase inhibitor, characterized by its ability to form covalent bonds with the active site serine residues of beta-lactamase enzymes. This interaction effectively blocks the hydrolysis of beta-lactam antibiotics, enhancing their stability. The compound's unique bicyclic structure allows for specific steric hindrance, which further impedes enzyme activity. Kinetic analyses demonstrate a competitive inhibition profile, highlighting its role in altering enzymatic reaction rates.

Phenoxymethylpenilloic Acid

4847-29-4sc-208165
10 mg
$300.00
(0)

Phenoxymethylpenilloic Acid functions as a beta-lactamase inhibitor through its ability to interact with the enzyme's active site, leading to the formation of stable acyl-enzyme complexes. This compound exhibits a distinctive structural configuration that enhances its affinity for beta-lactamase, effectively preventing substrate access. Its reaction kinetics reveal a non-competitive inhibition mechanism, showcasing its role in modulating enzymatic activity and prolonging the efficacy of beta-lactam antibiotics.

3-(Acetylthio)-2-benzylpropionic Acid

91702-98-6sc-209470
1 g
$220.00
(0)

3-(Acetylthio)-2-benzylpropionic Acid acts as a beta-lactamase inhibitor by forming covalent bonds with serine residues in the enzyme's active site, disrupting its catalytic function. The presence of the acetylthio group enhances its reactivity, allowing for rapid acylation and subsequent inactivation of the enzyme. This compound's unique steric and electronic properties facilitate selective binding, influencing the dynamics of enzyme-substrate interactions and altering the overall enzymatic pathway.