Date published: 2025-10-16

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Sulbactam (CAS 68373-14-8)

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Application:
Sulbactam is a β-lactamase inhibitor
CAS Number:
68373-14-8
Purity:
97%
Molecular Weight:
233.24
Molecular Formula:
C8H11NO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sulbactam, also known as Penicillanic acid sulfone, is extensively utilized in biochemical and microbiological research, particularly for its role in inhibiting certain bacterial enzymes. Researchers focus on its mechanism of action against beta-lactamase enzymes, which are produced by bacteria to confer resistance to beta-lactam antibiotics. By studying Sulbactam′s inhibitory effects, scientists aim to understand how it enhances the efficacy of beta-lactam antibiotics against resistant strains. This research is for developing more effective strategies in managing infections caused by resistant bacteria. Additionally, Sulbactam is used in enzymology studies to explore its interaction with other enzyme systems.


Sulbactam (CAS 68373-14-8) References

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  2. Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam.  |  Singh, GS. 2004. Mini Rev Med Chem. 4: 93-109. PMID: 14754446
  3. Sulbactam-containing beta-lactamase inhibitor combinations.  |  Akova, M. 2008. Clin Microbiol Infect. 14 Suppl 1: 185-8. PMID: 18154545
  4. Rational antibiotic therapy and the position of ampicillin/sulbactam.  |  Lode, HM. 2008. Int J Antimicrob Agents. 32: 10-28. PMID: 18539004
  5. Sulbactam/ampicillin, a new beta-lactamase inhibitor/beta-lactam antibiotic combination.  |  Benson, JM. and Nahata, MC. 1988. Drug Intell Clin Pharm. 22: 534-41. PMID: 3046887
  6. Sulbactam/ampicillin in paediatric infections.  |  Dajani, AS. 1988. Drugs. 35 Suppl 7: 35-8. PMID: 3065053
  7. Sulbactam: a beta-lactamase inhibitor.  |  Noguchi, JK. and Gill, MA. 1988. Clin Pharm. 7: 37-51. PMID: 3278833
  8. Cefoperazone/sulbactam: New composites against multiresistant gram negative bacteria?  |  Ku, YH. and Yu, WL. 2021. Infect Genet Evol. 88: 104707. PMID: 33418147
  9. Cefoperazone and sulbactam-related eosinophilic peritonitis: a case report and literature review.  |  Wang, Z., et al. 2021. J Int Med Res. 49: 3000605211025367. PMID: 34162261
  10. Evaluation of sulbactam and colistin/sulbactam efficacy against multiple resistant Acinetobacter baumannii blood isolates.  |  Heydarlou, MM., et al. 2022. Indian J Med Microbiol. 40: 567-571. PMID: 35817630
  11. Zidebactam restores sulbactam susceptibility against carbapenem-resistant Acinetobacter baumannii isolates.  |  Cedano, J., et al. 2022. Front Cell Infect Microbiol. 12: 918868. PMID: 35899052
  12. Bone Concentration of Ampicillin/Sulbactam: A Pilot Study in Patients with Osteonecrosis of the Jaw.  |  Straub, A., et al. 2022. Int J Environ Res Public Health. 19: PMID: 36429636
  13. The Pharmacokinetics/Pharmacodynamic Relationship of Durlobactam in Combination With Sulbactam in In Vitro and In Vivo Infection Model Systems Versus Acinetobacter baumannii-calcoaceticus Complex.  |  O'Donnell, JP. and Bhavnani, SM. 2023. Clin Infect Dis. 76: S202-S209. PMID: 37125469
  14. beta-Lactamase inhibition and in vitro activity of sulbactam and sulbactam/cefoperazone.  |  Williams, JD. 1997. Clin Infect Dis. 24: 494-7. PMID: 9114205

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sulbactam, 1 g

sc-272516
1 g
$80.00