Chemical inhibitors of BC006662 can exert their inhibitory effects through various molecular mechanisms, impacting the protein's activity within its signaling pathways. Staurosporine, a potent protein kinase inhibitor, can inhibit kinase activity that is essential for phosphorylation events, which may be crucial for BC006662 functionality. Similarly, Genistein's ability to inhibit tyrosine kinases can interfere with phosphorylation cascades that BC006662 may rely upon for its activation or regulatory functions. Bisindolylmaleimide I targets protein kinase C, whose inhibition could disrupt signaling pathways that converge on BC006662, leading to a decrease in its activity.
LY294002 and Wortmannin both inhibit PI3K, which is a pivotal component in many signaling pathways, including those regulating cell survival and growth that could involve BC006662. By inhibiting PI3K, these chemicals can prevent downstream signaling required for BC006662's activity. PD168393, by irreversibly inhibiting EGFR kinases, can block phosphorylation and subsequent signaling that may be necessary for the proper function of BC006662. PP2, which targets the Src family of kinases, can halt phosphorylation processes that might activate BC006662 directly or target proteins within its regulatory network.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Inhibits a broad spectrum of protein kinases, potentially inhibiting BC006662 activity through kinase regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Inhibits tyrosine kinases which could be involved in the activation or regulation of BC006662. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Selectively inhibits protein kinase C, possibly involved in signaling cascades regulating BC006662. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, which may play a role in signaling pathways that regulate BC006662 activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K/Akt pathway, potentially reducing BC006662 activity if it is PI3K/Akt dependent. | ||||||
Imatinib mesylate | 220127-57-1 | sc-202180 sc-202180A | 25 mg 100 mg | $44.00 $109.00 | 61 | |
Irreversibly inhibits EGFR kinases that may phosphorylate BC006662 or proteins in its pathway. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Inhibits Src family kinases that could phosphorylate BC006662 or associated proteins, thereby inhibiting its activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAP kinase which might be involved in the regulation of BC006662 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Selectively inhibits MEK1/2 which could be upstream regulators of BC006662 in the MAPK pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, possibly affecting BC006662 activity if it is part of the JNK signaling pathway. | ||||||