ASC2 inhibitors represent a class of chemical compounds with substantial relevance in molecular biology and cellular research due to their capacity to modulate a specific cellular process. These inhibitors predominantly target the activity of the ASC2 protein, which stands for Activating Signal Cointegrator 2. ASC2 is a crucial transcriptional coactivator that assumes a central role in the regulation of gene expression, effectively acting as a molecular switch for a multitude of cellular functions. It achieves this by interacting with transcription factors and other coactivators, thereby facilitating the transcription of specific genes. As a result, it influences a wide range of cellular processes such as cell proliferation, differentiation, and the response to various external signals.
The emergence of ASC2 inhibitors has significantly expanded our ability to unravel the complex web of molecular mechanisms that underlie gene regulation. These inhibitors operate by disrupting the interaction between ASC2 and its binding partners, consequently modifying the transcriptional activity of the targeted genes. This selective interference allows researchers to investigate the molecular basis of diseases, as aberrant gene expression often lies at the heart of various pathological conditions. Their capacity to provide valuable insights into potential targets and a deeper understanding of cellular processes at the molecular level holds the promise of future advancements in biomedicine.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Inhibits cyclooxygenase enzymes (COX-1 and COX-2) to reduce prostaglandin synthesis, thereby decreasing inflammation and pain. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $52.00 $86.00 | 6 | |
Blocks the activity of COX-1 and COX-2, reducing prostaglandin production and alleviating pain and inflammation. | ||||||
Omeprazole | 73590-58-6 | sc-202265 | 50 mg | $66.00 | 4 | |
Inhibits the proton pump (H+/K+ ATPase) in gastric parietal cells, reducing gastric acid secretion. | ||||||
Cimetidine | 51481-61-9 | sc-202996 sc-202996A | 5 g 10 g | $62.00 $86.00 | 1 | |
Competitively inhibits histamine H2 receptors, reducing stomach acid production and used for acid-related conditions. | ||||||
Allopurinol | 315-30-0 | sc-207272 | 25 g | $128.00 | ||
Inhibits xanthine oxidase, reducing the production of uric acid and preventing gout attacks by lowering uric acid levels in the blood. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Activates AMP-activated protein kinase (AMPK), which leads to improved insulin sensitivity and lower glucose production in the liver. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Acts as a selective estrogen receptor modulator (SERM), blocking estrogen receptors in breast tissue. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Inhibits tyrosine kinases, particularly BCR-ABL and c-KIT, to target the abnormal signaling pathways in cancer cells. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Targets multiple kinases, including Raf kinases, VEGFR, and PDGFR, to inhibit angiogenesis and cell proliferation in cancer therapy. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Inhibits the epidermal growth factor receptor (EGFR) tyrosine kinase, disrupting the signaling cascade in cancer cells. |