ASAH2C Inhibitors
ASAH2C Inhibitors could be envisioned as a distinctive class of chemical compounds designed to modulate cellular processes by selectively targeting ASAH2C, an enzyme with potential roles in lipid metabolism. ASAH2C is a member of the acid ceramidase family and is involved in the hydrolysis of ceramides, lipid molecules with regulatory functions in various cellular processes. The inhibitors might exert their effects by binding specifically to ASAH2C, interfering with its enzymatic activity. This interference could lead to alterations in the ceramide metabolism, influencing downstream cellular functions.
The putative mechanism of action for ASAH2C Inhibitors might involve the prevention of ceramide hydrolysis or the modulation of ASAH2C's catalytic activity. By selectively inhibiting ASAH2C, these compounds could impact the delicate balance of ceramide levels within cells, potentially influencing cellular processes such as cell signaling, apoptosis, or lipid homeostasis. Understanding the structure-activity relationships of ASAH2C Inhibitors would be crucial for optimizing their selectivity and efficacy. This description underscores the potential significance of exploring novel chemical classes to elucidate the roles of enzymes like ASAH2C in cellular lipid metabolism. Further research would be necessary to provide accurate and detailed information about any potential ASAH2C Inhibitors and their effects on cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and inhibits RNA polymerase, which could decrease transcription of the ASAH2C gene. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Prevents protein synthesis by inhibiting the translocation step in eukaryotic ribosomes, potentially reducing ASAH2C levels. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits the mTOR pathway, which is involved in protein synthesis and could lead to reduced expression of ASAH2C. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Affects DNA methylation, potentially altering the gene expression pattern including that of ASAH2C. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylase, changing chromatin structure and potentially decreasing ASAH2C expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Specifically inhibits RNA polymerase II, which could lead to reduced transcription of ASAH2C. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, potentially affecting nucleotide synthesis and ASAH2C mRNA production. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits protein synthesis by affecting peptide bond formation on ribosomes, which could decrease ASAH2C production. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I, necessary for DNA replication and transcription, potentially affecting ASAH2C expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II, potentially decreasing the transcription of the ASAH2C gene. | ||||||