The class of Arrestin-C activators comprises a variety of chemical compounds that can indirectly influence the activity of Arrestin-C (ARR3) through their effects on GPCR signaling pathways and related cellular processes. This group includes molecules such as Forskolin and Caffeine, which can modulate cAMP levels, potentially affecting GPCR signaling and thereby influencing ARR3 activity. These compounds can impact the regulatory mechanisms of GPCRs, with which ARR3 interacts.
Other compounds in this class, like Retinoic Acid and Vitamin A, are crucial for phototransduction pathways, especially in retinal cells where ARR3 plays a significant role. The modulation of these pathways could potentially influence ARR3 activity in the context of vision. Curcumin, Resveratrol, and Epigallocatechin Gallate (EGCG), known for their effects on various cellular signaling pathways, including those related to aging and metabolism, might also modulate ARR3 activity. Antioxidants like Quercetin, are integral to this class for their potential roles in modulating GPCR dynamics and cellular signaling environments. Sulforaphane and Zinc, affecting gene expression and cellular signaling, could also have an indirect effect on ARR3 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases cAMP levels, potentially modulating GPCR signaling pathways and indirectly influencing ARR3 activity. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A phosphodiesterase inhibitor; may increase cAMP levels and affect GPCR signaling, potentially impacting ARR3. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression and phototransduction pathways, potentially modulating ARR3 activity in retinal cells. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Affects various signaling pathways; could indirectly influence ARR3 by altering GPCR signaling dynamics. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences sirtuin and AMPK pathways; may modulate ARR3 activity through pathways related to aging and metabolic regulation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Affects gene expression and cellular signaling; may indirectly influence ARR3 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences metabolic and inflammatory pathways; could indirectly modulate ARR3 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with antioxidant properties; may influence ARR3 by affecting cellular signaling pathways. | ||||||
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $385.00 $2654.00 | ||
Essential for vision and phototransduction; could influence ARR3 activity in the retina. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Important for cellular signaling and enzyme function; may indirectly influence ARR3 activity. | ||||||