Date published: 2026-5-15

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Arrestin-C Activators

The class of Arrestin-C activators comprises a variety of chemical compounds that can indirectly influence the activity of Arrestin-C (ARR3) through their effects on GPCR signaling pathways and related cellular processes. This group includes molecules such as Forskolin and Caffeine, which can modulate cAMP levels, potentially affecting GPCR signaling and thereby influencing ARR3 activity. These compounds can impact the regulatory mechanisms of GPCRs, with which ARR3 interacts.

Other compounds in this class, like Retinoic Acid and Vitamin A, are crucial for phototransduction pathways, especially in retinal cells where ARR3 plays a significant role. The modulation of these pathways could potentially influence ARR3 activity in the context of vision. Curcumin, Resveratrol, and Epigallocatechin Gallate (EGCG), known for their effects on various cellular signaling pathways, including those related to aging and metabolism, might also modulate ARR3 activity. Antioxidants like Quercetin, are integral to this class for their potential roles in modulating GPCR dynamics and cellular signaling environments. Sulforaphane and Zinc, affecting gene expression and cellular signaling, could also have an indirect effect on ARR3 activity.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Increases cAMP levels, potentially modulating GPCR signaling pathways and indirectly influencing ARR3 activity.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

A phosphodiesterase inhibitor; may increase cAMP levels and affect GPCR signaling, potentially impacting ARR3.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Influences gene expression and phototransduction pathways, potentially modulating ARR3 activity in retinal cells.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Affects various signaling pathways; could indirectly influence ARR3 by altering GPCR signaling dynamics.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Influences sirtuin and AMPK pathways; may modulate ARR3 activity through pathways related to aging and metabolic regulation.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Affects gene expression and cellular signaling; may indirectly influence ARR3 activity.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Influences metabolic and inflammatory pathways; could indirectly modulate ARR3 activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

A flavonoid with antioxidant properties; may influence ARR3 by affecting cellular signaling pathways.

Vitamin A

68-26-8sc-280187
sc-280187A
1 g
10 g
$385.00
$2654.00
(2)

Essential for vision and phototransduction; could influence ARR3 activity in the retina.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Important for cellular signaling and enzyme function; may indirectly influence ARR3 activity.