Items 261 to 261 of 261 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicinol | 54193-28-1 | sc-495904 sc-495904A | 2.5 mg 25 mg | $357.00 $2497.00 | 4 | |
Doxorubicinol, a metabolite of doxorubicin, exhibits unique interactions with DNA, intercalating between base pairs and disrupting replication processes. This compound stabilizes the topoisomerase II-DNA complex, preventing the re-ligation of DNA strands and leading to double-strand breaks. Its distinct physicochemical properties enhance cellular uptake, while its reactive nature facilitates interactions with various biomolecules, influencing cellular redox states and contributing to its antineoplastic activity. | ||||||