α3e Tubulin Inhibitors could be envisioned as a unique category of chemical compounds designed to interfere with cellular processes by selectively targeting the α3e domain of tubulin. Tubulins are fundamental building blocks of microtubules, dynamic structures that play crucial roles in maintaining cell shape, intracellular transport, and cell division. The α3e domain, a region within tubulin, might be crucial for microtubule stability and dynamics. α3e Tubulin Inhibitors could potentially exert their effects by binding selectively to this domain, disrupting the normal polymerization and depolymerization of tubulin into microtubules.
The mechanistic action of α3e Tubulin Inhibitors, if they were to exist, might involve interference with microtubule dynamics, impacting essential cellular processes. By selectively targeting the α3e domain, these inhibitors could induce conformational changes in tubulin, potentially affecting its ability to form stable microtubules. Exploring the structure-activity relationships of such inhibitors could be crucial in understanding their specificity and efficacy, providing insights into the regulation of microtubule dynamics within cells. It's important to note that further research and developments in the field would be necessary to provide accurate and detailed information about any potential α3e Tubulin Inhibitors.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and inhibits RNA polymerase, potentially decreasing tubulin mRNA synthesis. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis by interfering with the translocation step in protein elongation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Binds to mTOR and inhibits its pathway, which can downregulate protein synthesis including tubulin. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Incorporates into DNA and RNA, inhibits DNA methyltransferase, potentially affecting gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylase, altering chromatin structure and affecting gene expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, leading to decreased mRNA synthesis for many proteins, including tubulin. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, leading to depleted guanine nucleotides and reduced RNA synthesis. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits peptidyl transferase activity of the 60S ribosomal subunit, preventing protein synthesis. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I, leading to reduced transcription and potential downregulation of gene expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II transcriptional elongation and could decrease tubulin mRNA levels. |