ALDH3B2 activators encompass a collection of compounds that can, either directly or indirectly, stimulate the enzymatic function of ALDH3B2, a specific isoenzyme within the aldehyde dehydrogenase family. One fundamental compound is NAD+, an indispensable cofactor that elevates the activity of ALDH enzymes by facilitating the oxidation of aldehydes.
Compounds like Sulforaphane and Alda-1 have been documented to upregulate various ALDH isoforms, suggesting an influence on ALDH3B2. In contrast, agents like Retinoic acid work more covertly, modulating ALDH activity at the transcriptional level, possibly influencing ALDH3B2. The relationship between aldehyde dehydrogenase enzymes and certain phytochemicals is also noteworthy. For instance, Resveratrol, Curcumin, and Genistein have shown interactions with ALDHs through various cellular pathways, suggesting a modulation of ALDH3B2. The connection of ALDH activity to broader cellular signaling pathways is also highlighted by compounds like Forskolin, which operates via the cAMP pathway. The diverse nature of these activators underlines the complex regulatory landscape governing ALDH3B2's function within the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
Essential cofactor for ALDH enzymes, increasing their activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Known to upregulate various ALDH isoenzymes, potentially influencing ALDH3B2 activity. | ||||||
Alda 1 | 349438-38-6 | sc-479867 | 50 mg | $300.00 | ||
An activator for several ALDH isoenzymes, may also increase ALDH3B2 activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Affects ALDH enzymes indirectly through transcriptional modulation; may influence ALDH3B2. | ||||||
Daidzin | 552-66-9 | sc-202123 sc-202123A | 1 mg 5 mg | $72.00 $137.00 | 1 | |
An inhibitor for some ALDHs, but in specific contexts, may upregulate other isoforms. | ||||||
Oleanolic Acid | 508-02-1 | sc-205775 sc-205775A | 100 mg 500 mg | $86.00 $302.00 | 8 | |
Can affect ALDH activity in certain cell types, potentially impacting ALDH3B2. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Known to affect ALDH activity via cAMP pathway, potentially modulating ALDH3B2 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences ALDH enzymes through various cellular pathways, potentially affecting ALDH3B2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known to modulate ALDH activity in certain settings, which may indirectly affect ALDH3B2. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Influences ALDH activity, potentially impacting ALDH3B2. | ||||||