ALCAM Inhibitors

ALCAM (Activated Leukocyte Cell Adhesion Molecule), also known as CD166, is a cell surface glycoprotein belonging to the immunoglobulin superfamily. ALCAM plays a crucial role in various cellular processes, primarily by mediating cell-cell adhesion and promoting cell migration. ALCAM is widely expressed in different tissues and cell types, including leukocytes, neurons, and endothelial cells. In recent years, researchers have identified a class of compounds known as ALCAM inhibitors, which are designed to modulate the function of this cell adhesion molecule. ALCAM inhibitors are chemical compounds or biologics that target ALCAM and interfere with its activity. These inhibitors work by binding to specific regions on ALCAM's extracellular domain, preventing its interaction with other cell surface molecules or extracellular ligands. By inhibiting ALCAM, these compounds can impact various physiological and pathological processes where ALCAM-mediated cell adhesion and signaling play a role. ALCAM inhibitors have garnered attention in the field of research for their ability to influence cell migration, immune cell activation, and neural development, among other cellular events.