AEBP2 inhibitors are a class of chemical compounds specifically designed to target and modulate the activity of the Adipocyte Enhancer-Binding Protein 2 (AEBP2). AEBP2 is a critical transcriptional co-regulator that plays a pivotal role in gene expression regulation, particularly in the context of adipocyte differentiation and lipid metabolism. These inhibitors are developed with the primary objective of disrupting the function of AEBP2, leading to alterations in the gene expression patterns associated with various cellular processes, primarily those related to adipogenesis and adipocyte homeostasis.
AEBP2 inhibitors typically function by binding to the AEBP2 protein and interfering with its ability to interact with other transcriptional factors and co-regulators. By doing so, they can modulate the expression of genes involved in adipocyte development and lipid metabolism, potentially leading to changes in fat storage and adipose tissue function. These chemical entities have garnered attention in the realm of scientific research as they offer a valuable tool for dissecting the molecular mechanisms underlying adipogenesis and lipid regulation, aiding in a better understanding of metabolic disorders and obesity-related conditions. Researchers utilize AEBP2 inhibitors in cellular and molecular studies to investigate the role of AEBP2 in gene expression and its broader impact on cellular physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GSK343 | 1346704-33-3 | sc-397025 sc-397025A | 5 mg 25 mg | $151.00 $461.00 | 1 | |
Selective EZH2 inhibitor that reduces H3K27me3 levels, thus potentially altering the functions of PRC2-associated AEBP2. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
Inhibits EZH2, causing a decrease in H3K27me3, which could influence AEBP2 function within PRC2. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
Inhibits EZH2 and EZH1, affecting H3K27me3 levels and possibly influencing the role of AEBP2 in gene repression. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $92.00 $243.00 $306.00 | ||
Highly selective EZH2 inhibitor that diminishes H3K27me3 levels, potentially impacting AEBP2's contribution to PRC2. | ||||||
Epz004777 | 1338466-77-5 | sc-507560 | 100 mg | $575.00 | ||
Inhibits DOT1L, affecting H3K79 methylation, which may influence chromatin states regulating AEBP2's role in gene repression. | ||||||
MS023 | 1831110-54-3 | sc-507463 | 5 mg | $165.00 | ||
Inhibits type I PRMTs, altering the methylation status of arginine residues on histones and potentially affecting AEBP2. | ||||||