Adenosine deaminase activators encompass a diverse group of compounds that modulate the enzyme's activity either directly or indirectly. These chemicals, through various mechanisms, impact adenosine metabolism and cellular processes, resulting in the activation of adenosine deaminase. Among these activators, nucleotides such as Adenosine Monophosphate (AMP) and Guanosine Monophosphate (GMP) indirectly influence adenosine deaminase by promoting the accumulation of its substrate, adenosine. Additionally, coenzymes like Nicotinamide Adenine Dinucleotide (NAD) and Nicotinamide Adenine Dinucleotide Phosphate (NADP) indirectly activate adenosine deaminase by influencing cellular redox status.
Nucleosides, including Inosine and 2'-Deoxyadenosine (dAdo), indirectly activate adenosine deaminase by mimicking the structure of its substrate, promoting substrate availability. Natural substrates such as Adenosine and 5'-Methylthioadenosine (MTA) activate adenosine deaminase through feedback mechanisms, impacting cellular processes influenced by adenosine metabolism. The nucleotide Adenosine Triphosphate (ATP) indirectly activates adenosine deaminase by modulating cellular energy status, impacting enzyme activation. Similarly, 2'-Deoxyadenosine 5'-Diphosphate (dADP) and Guanosine Triphosphate (GTP) indirectly influence adenosine deaminase by influencing substrate availability and cellular processes. In summary, adenosine deaminase activators constitute a diverse array of compounds that modulate the enzyme's activity either directly or indirectly. These activators offer insights into the regulatory mechanisms governing adenosine deaminase activation and its impact on cellular processes influenced by adenosine metabolism.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
Adenosine Triphosphate (ATP), a crucial cellular energy carrier, indirectly activates adenosine deaminase by influencing cellular energy status. ATP modulation leads to altered cellular conditions, promoting the activation of adenosine deaminase and subsequent effects on adenosine metabolism. | ||||||
Adenosine-5′-Diphosphate, free acid | 58-64-0 | sc-291846 sc-291846A sc-291846B sc-291846C sc-291846D sc-291846E | 100 mg 500 mg 1 g 10 g 100 g 500 g | $79.00 $184.00 $348.00 $942.00 $4688.00 $9370.00 | 1 | |
2'-Deoxyadenosine 5'-Diphosphate (dADP), a nucleotide, indirectly activates adenosine deaminase by influencing the availability of its substrate, adenosine. The presence of dADP promotes substrate accumulation, enhancing adenosine deaminase activation through a feedback mechanism within cellular processes. | ||||||
Guanosine-5′-monophosphate | 85-32-5 | sc-295032 sc-295032A sc-295032B | 1 g 2.5 g 5 g | $322.00 $622.00 $1051.00 | 5 | |
Guanosine Monophosphate (GMP), a nucleotide, indirectly activates adenosine deaminase by influencing the levels of its substrate, adenosine. Increased GMP levels lead to enhanced substrate availability, promoting the activation of adenosine deaminase through intricate cellular mechanisms. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
Nicotinamide Adenine Dinucleotide (NAD), a coenzyme involved in cellular redox reactions, indirectly activates adenosine deaminase. NAD's influence on cellular redox status promotes the activation of adenosine deaminase through complex interactions within cellular signaling pathways, impacting adenosine metabolism. | ||||||
Inosine | 58-63-9 | sc-295182 sc-295182A | 1 g 5 g | $60.00 $92.00 | ||
Inosine, a nucleoside, indirectly activates adenosine deaminase by influencing its substrate, adenosine. Elevated inosine levels promote the accumulation of adenosine, leading to enhanced activation of adenosine deaminase through feedback mechanisms within cellular processes. | ||||||
Guanosine | 118-00-3 | sc-218575 sc-218575A sc-218575B sc-218575C sc-218575D | 5 g 25 g 250 g 1 kg 5 kg | $40.00 $50.00 $84.00 $250.00 $1103.00 | ||
Guanosine, a nucleoside, indirectly activates adenosine deaminase by influencing the levels of its substrate, adenosine. Increased guanosine levels lead to enhanced substrate availability, promoting the activation of adenosine deaminase through intricate cellular processes. | ||||||
β-Nicotinamide adenine dinucleotide phosphate | 53-59-8 | sc-215560 sc-215560A | 100 mg 250 mg | $182.00 $319.00 | ||
Nicotinamide Adenine Dinucleotide Phosphate (NADP), a coenzyme involved in cellular redox reactions, indirectly activates adenosine deaminase. NADP's impact on cellular redox status promotes the activation of adenosine deaminase through complex interactions within cellular signaling pathways, influencing adenosine metabolism. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine, the natural substrate of adenosine deaminase, activates the enzyme through a feedback mechanism. Increased adenosine levels enhance the activation of adenosine deaminase, providing a regulatory mechanism within cellular processes influenced by adenosine metabolism. | ||||||
5′-Deoxy-5′-methylthioadenosine | 2457-80-9 | sc-202427 | 50 mg | $122.00 | 1 | |
5'-Methylthioadenosine (MTA), an adenosine analog, indirectly activates adenosine deaminase by influencing substrate availability. The incorporation of MTA into cellular processes promotes substrate accumulation, enhancing the activation of adenosine deaminase through feedback mechanisms within intricate cellular pathways. | ||||||
Guanosine 5′-Triphosphate, Disodium Salt | 56001-37-7 | sc-295030 sc-295030A | 50 mg 250 mg | $166.00 $327.00 | ||
Guanosine Triphosphate (GTP), a nucleotide, indirectly activates adenosine deaminase by influencing cellular processes and substrate availability. The presence of GTP promotes the accumulation of adenosine, leading to enhanced activation of adenosine deaminase through feedback mechanisms within cellular pathways. | ||||||