Date published: 2026-6-8

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Acrogranin Inhibitors

Acrogranin inhibitors constitute a class of compounds that either directly target acrogranin or indirectly modulate its activity by disrupting key signaling pathways. Sorafenib, a multikinase inhibitor, directly targets Raf kinases and indirectly modulates acrogranin by disrupting the MAPK/ERK signaling pathway. Sorafenib-induced Raf inhibition leads to downstream effects on the MAPK/ERK pathway, influencing acrogranin expression and function in cellular processes. U0126, a MEK inhibitor, indirectly influences acrogranin by disrupting the MAPK/ERK signaling pathway. U0126-induced MEK inhibition leads to altered phosphorylation cascades, affecting acrogranin expression and function. PD98059, another selective MEK inhibitor, similarly modulates acrogranin by disrupting the MAPK/ERK signaling pathway. BAY 86-9766, CI-1040, Selumetinib, and FR180204 all belonging to the MEK or ERK inhibitor class, indirectly influence acrogranin by disrupting the MAPK/ERK signaling pathway. These inhibitors alter phosphorylation cascades, affecting acrogranin expression and function in various cellular processes. SCH772984 and AZD6244 are additional compounds that directly target ERK, further contributing to the modulation of acrogranin-related cellular processes. This diverse array of acrogranin inhibitors provides a comprehensive toolkit for researchers studying the intricate regulatory pathways involved in acrogranin function.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Sorafenib is a multikinase inhibitor that directly targets Raf kinases and indirectly modulates acrogranin by disrupting the MAPK/ERK signaling pathway. Sorafenib-induced Raf inhibition leads to downstream effects on the MAPK/ERK pathway, influencing acrogranin expression and function in cellular processes.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 is a MEK inhibitor that indirectly influences acrogranin by disrupting the MAPK/ERK signaling pathway. U0126-induced MEK inhibition leads to altered phosphorylation cascades, affecting acrogranin expression and function in cellular processes.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

PD98059 is a selective MEK inhibitor that indirectly modulates acrogranin by disrupting the MAPK/ERK signaling pathway. PD98059-induced MEK inhibition leads to altered phosphorylation cascades, affecting acrogranin expression and function in cellular processes.

BAY 869766

923032-37-5sc-364427
sc-364427A
5 mg
10 mg
$245.00
$428.00
1
(1)

BAY 86-9766 is a Raf kinase inhibitor that directly targets the MAPK/ERK signaling pathway, influencing acrogranin expression and function. BAY 86-9766-induced Raf inhibition leads to downstream effects on the MAPK/ERK pathway, modulating acrogranin-related cellular processes.

PD 184,352

212631-79-3sc-202759
sc-202759A
1 mg
5 mg
$40.00
$260.00
34
(1)

PD 184,352 is a selective MEK inhibitor that indirectly modulates acrogranin by disrupting the MAPK/ERK signaling pathway. CI-1040-induced MEK inhibition leads to altered phosphorylation cascades, affecting acrogranin expression and function in cellular processes.

Selumetinib

606143-52-6sc-364613
sc-364613A
sc-364613B
sc-364613C
sc-364613D
5 mg
10 mg
100 mg
500 mg
1 g
$29.00
$82.00
$420.00
$1897.00
$3021.00
5
(1)

Selumetinib is a selective MEK inhibitor that indirectly influences acrogranin by disrupting the MAPK/ERK signaling pathway. Selumetinib-induced MEK inhibition leads to altered phosphorylation cascades, affecting acrogranin expression and function in cellular processes.

SCH772984

942183-80-4sc-473205
5 mg
$370.00
5
(0)

SCH772984 is a selective ERK inhibitor that directly targets the MAPK/ERK signaling pathway, influencing acrogranin expression and function. SCH772984-induced ERK inhibition leads to downstream effects on the MAPK/ERK pathway, modulating acrogranin-related cellular processes.

ERK Inhibitor II, FR180204

865362-74-9sc-203945
sc-203945A
sc-203945B
sc-203945C
1 mg
5 mg
10 mg
50 mg
$110.00
$165.00
$239.00
$942.00
45
(2)

FR180204 is a selective ERK inhibitor that directly targets the MAPK/ERK signaling pathway, influencing acrogranin expression and function. FR180204-induced ERK inhibition leads to downstream effects on the MAPK/ERK pathway, modulating acrogranin-related cellular processes.