Date published: 2025-9-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 151 to 160 of 374 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sulforhodamine 101 acid chloride

82354-19-6sc-215930
sc-215930A
10 mg
25 mg
$173.00
$438.00
(1)

Sulforhodamine 101 acid chloride, an acid halide, is characterized by its vibrant chromophore, which imparts distinct optical properties. The presence of the acid chloride functional group enhances its reactivity, facilitating rapid acylation with nucleophiles. Its unique structure allows for specific interactions with various substrates, leading to selective transformations. Additionally, the compound's solubility in organic solvents influences its kinetics, making it a versatile reagent in synthetic pathways.

2-(4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)ethanesulfonyl fluoride

sc-339996
sc-339996A
250 mg
1 g
$288.00
$584.00
(0)

2-(4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)ethanesulfonyl fluoride, as an acid halide, exhibits remarkable electrophilic behavior due to the presence of the sulfonyl fluoride moiety. This feature promotes swift nucleophilic attack, enabling efficient acylation reactions. The compound's unique thieno-pyrimidine framework contributes to its distinct reactivity profile, allowing for selective interactions with a range of nucleophiles. Its stability in various solvents further enhances its utility in diverse synthetic applications.

2,6-dichloro-3-methylbenzenesulfonyl chloride

sc-343523
sc-343523A
1 g
5 g
$510.00
$1455.00
(0)

2,6-Dichloro-3-methylbenzenesulfonyl chloride, as an acid halide, showcases exceptional reactivity stemming from its sulfonyl chloride group, which acts as a potent electrophile. This compound facilitates rapid acylation processes, particularly with amines and alcohols, leading to the formation of sulfonamides and esters. The presence of chlorine substituents enhances its electrophilic character, allowing for selective and efficient reactions under mild conditions, making it a versatile intermediate in organic synthesis.

Methyl 3-(chlorocarbonyl)benzoate

3441-03-0sc-235713
1 g
$408.00
(0)

Methyl 3-(chlorocarbonyl)benzoate, functioning as an acid halide, exhibits remarkable reactivity due to its chlorocarbonyl moiety, which serves as a strong electrophile. This compound readily engages in nucleophilic acyl substitution, enabling the formation of esters and amides with various nucleophiles. Its unique structure allows for regioselective reactions, influenced by steric and electronic factors, making it a valuable intermediate in diverse synthetic pathways.

3-Fluorobenzoyl chloride

1711-07-5sc-231716
sc-231716A
5 g
25 g
$21.00
$66.00
(0)

3-Fluorobenzoyl chloride, as an acid halide, showcases distinctive reactivity attributed to its fluorinated aromatic ring, which enhances electrophilicity and alters reaction dynamics. The presence of the fluorine atom can influence the stability of intermediates during nucleophilic acyl substitution, leading to unique selectivity patterns. This compound's ability to participate in acylation reactions with various nucleophiles is further enhanced by its polar nature, facilitating rapid reaction kinetics and diverse synthetic applications.

3-Chloropropanesulfonyl Chloride

1633-82-5sc-216426
5 g
$68.00
(0)

3-Chloropropanesulfonyl chloride, an acid halide, exhibits remarkable reactivity due to its sulfonyl group, which enhances electrophilic character and facilitates nucleophilic attack. The presence of chlorine introduces steric effects that can influence reaction pathways, leading to distinct selectivity in acylation processes. Its polar nature promotes solubility in various solvents, allowing for efficient interaction with nucleophiles and accelerating reaction rates, making it a versatile intermediate in organic synthesis.

4-methoxynaphthalene-1-sulfonyl chloride

56875-55-9sc-352490
sc-352490A
250 mg
1 g
$197.00
$399.00
(0)

4-Methoxynaphthalene-1-sulfonyl chloride, as an acid halide, showcases unique reactivity stemming from its naphthalene structure, which provides a planar, aromatic system that stabilizes transition states during nucleophilic acyl substitution. The methoxy group enhances electron density, influencing the electrophilicity of the sulfonyl chloride. This compound's ability to engage in rapid acylation reactions is further augmented by its favorable solvation properties, promoting efficient interactions with various nucleophiles.

methyl 4-bromo-3-(chlorosulfonyl)benzoate

sc-353949
sc-353949A
250 mg
1 g
$197.00
$399.00
(0)

Methyl 4-bromo-3-(chlorosulfonyl)benzoate, as an acid halide, exhibits distinctive reactivity due to its electron-withdrawing bromine and chlorosulfonyl groups, which enhance its electrophilic character. The presence of the sulfonyl moiety facilitates strong dipole interactions, promoting rapid acylation with nucleophiles. Its unique steric and electronic properties allow for selective reactions, making it a versatile intermediate in various synthetic pathways.

4-isopropoxy-3-methylbenzenesulfonyl chloride

sc-352438
sc-352438A
250 mg
1 g
$197.00
$399.00
(0)

4-Isopropoxy-3-methylbenzenesulfonyl chloride, as an acid halide, showcases remarkable reactivity stemming from its isopropoxy group, which influences steric hindrance and electronic distribution. This compound's sulfonyl chloride functionality enhances its electrophilicity, enabling swift acylation reactions with nucleophiles. The interplay of sterics and electronics allows for tailored reactivity, making it a key player in diverse synthetic transformations and facilitating unique reaction pathways.

2-chloro-6-methoxyquinoline-5-sulfonyl chloride

sc-341800
sc-341800A
250 mg
1 g
$288.00
$584.00
(0)

2-Chloro-6-methoxyquinoline-5-sulfonyl chloride, as an acid halide, exhibits distinctive reactivity due to its quinoline structure, which introduces aromatic stabilization and influences nucleophilic attack. The presence of the sulfonyl chloride group enhances its electrophilic character, promoting rapid acylation with various nucleophiles. Its unique molecular architecture allows for selective functionalization, enabling intricate synthetic strategies and diverse reaction mechanisms in organic synthesis.