AChR Inhibitors
Santa Cruz Biotechnology now offers a broad range of AChR Inhibitors. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. AChR Inhibitors offered by Santa Cruz inhibit AChR and, in some cases, other ligand-gated ion channel receptor and neurotransmitter related proteins. View detailed AChR Inhibitor specifications, including AChR Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 21 to 25 of 25 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Hyoscyamine | 101-31-5 | sc-295290 sc-295290A | 1 g 5 g | $218.00 $400.00 | ||
L-Hyoscyamine is a potent alkaloid that exhibits selective antagonism at acetylcholine receptors (AChRs), characterized by its ability to induce conformational shifts in receptor structure. This compound engages in specific ionic and hydrophobic interactions, which modulate receptor activity and influence neurotransmission pathways. Its stereochemistry plays a crucial role in binding affinity, while its lipophilicity enhances membrane permeability, facilitating rapid receptor engagement and signaling modulation. | ||||||
Mecamylamine Hydrochloride | 826-39-1 | sc-205742 sc-205742A | 5 mg 25 mg | $82.00 $260.00 | 3 | |
Mecamylamine Hydrochloride is a unique compound that acts as a non-selective antagonist at acetylcholine receptors (AChRs). Its molecular structure allows for versatile interactions with receptor sites, influencing ion channel dynamics and neurotransmitter release. The compound's ability to disrupt the conformational equilibrium of AChRs alters synaptic transmission. Additionally, its hydrophilic nature enhances solubility in biological systems, affecting its distribution and interaction kinetics within neural pathways. | ||||||
Cisatracurium besylate | 96946-42-8 | sc-357315 | 100 mg | $306.00 | ||
Cisatracurium besylate is a neuromuscular blocking agent that selectively inhibits acetylcholine receptors (AChRs) at the neuromuscular junction. Its unique structure facilitates a rapid onset of action through competitive antagonism, effectively preventing muscle contraction. The compound undergoes a process of spontaneous degradation, which contributes to its predictable pharmacokinetics. This characteristic allows for a shorter duration of action, making it distinct in its interaction with AChRs compared to other agents. | ||||||
4-Diphenylacetoxy-N-(2-chloroethyl)piperidine hydrochloride | 130817-71-9 | sc-252148 sc-252148A | 25 mg 100 mg | $250.00 $850.00 | ||
4-Diphenylacetoxy-N-(2-chloroethyl)piperidine hydrochloride functions as a selective modulator of acetylcholine receptors (AChRs), characterized by its unique diphenylacetoxy moiety that facilitates specific receptor interactions. This compound exhibits a distinctive allosteric modulation, altering receptor dynamics and ion permeability. Its chlorinated ethyl group enhances hydrophobic interactions, influencing binding affinity and kinetics, while promoting a nuanced response in synaptic signaling pathways. | ||||||
Chlorisondamine diiodide | 96750-66-2 | sc-500792 sc-500792A | 10 mg 50 mg | $150.00 $560.00 | ||
Chlorisondamine diiodide acts as a potent antagonist of acetylcholine receptors (AChRs), exhibiting unique binding dynamics that alter receptor conformation. Its diiodide substituents enhance lipophilicity, promoting efficient membrane penetration. The compound's interaction with AChRs leads to a distinct modulation of ion channel activity, influencing synaptic transmission. Additionally, its reaction kinetics reveal a rapid association and dissociation profile, distinguishing it from other AChR antagonists. | ||||||