Mecamylamine Hydrochloride CAS: 826-39-1
MF: C11H21N•HCl
MW: 203.75
A noncompetitive nicotinic AChR inhibitor.

Mecamylamine Hydrochloride (CAS 826-39-1)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 135ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: 2-(Methylamino)isocamphane hydrochloride
Application: Mecamylamine Hydrochloride is a noncompetitive nicotinic AChR inhibitor
CAS Number: 826-39-1
Molecular Weight: 203.75
Molecular Formula: C11H21N•HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Mecamylamine Hydrochloride is a noncompetitive and nonselective antagonist of AChRs. The compound preferentially blocks nicotinic receptors at autonomic ganglia and is able to cross the blood brain barrier. Once across the blood brain barrier Mecamylamine Hydrochloride can selectively antagonize neuronal AChRs. Mecamylamine Hydrochloride is an inhibitor of AChR α 3, AChR α 4, AChR α 7 and AChRβ2.


1. Rodgers, R.J. 1979. Psychopharmacology. 66: 93-98. PMID: 120548
2. Young, J.M., et al. 2001. Clin Ther. 23: 532-565. PMID: 11354389
3. Bacher, I., et al. 2009. Expert Opin Pharmacother. 10: 2709-2721. PMID: 19874251

Physical State :
Storage :
Store at room temperature
Melting Point :
245.5-246.5° C (dec.)
Boiling Point :
189.3° C at 760 mmHg (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
EC Number :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Mecamylamine Hydrochloride (CAS 826-39-1)  Product Citations

See how others have used Mecamylamine Hydrochloride (CAS 826-39-1). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 26803847  Wong, MK. et al. 2016. Toxicological sciences : an official journal of the Society of Toxicology. 151: 23-34.

PMID: # 31580752  J Med Food. 388-394.

Citations 1 to 2 of 2 total

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Mecamylamine Hydrochloride, sc-205742, is lyophilized powder.
Answered by: Chemical Support 4
Date published: 2017-04-06
  • y_2020, m_11, d_24, h_16CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.12
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_205742, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 106ms
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.