AChR α 3 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytisine | 485-35-8 | sc-203015 sc-203015A | 5 mg 25 mg | $56.00 $190.00 | ||
Cytisine acts as a selective agonist at the alpha-3 nicotinic acetylcholine receptor subtype, engaging in specific hydrogen bonding and hydrophobic interactions that stabilize receptor activation. Its unique binding profile promotes distinct conformational shifts, enhancing ion channel permeability. The compound exhibits notable reaction kinetics, characterized by a relatively fast association rate, which influences synaptic signaling pathways and receptor desensitization dynamics. | ||||||
LY 2087101 | 913186-74-0 | sc-361235 sc-361235A | 10 mg 50 mg | $159.00 $645.00 | ||
LY 2087101 selectively targets the alpha-3 nicotinic acetylcholine receptor, exhibiting a unique binding affinity that facilitates specific electrostatic interactions. This compound induces conformational changes that modulate receptor activity, influencing downstream signaling cascades. Its kinetic profile reveals a rapid dissociation rate, which plays a crucial role in receptor recycling and functional modulation. The compound's distinct molecular interactions contribute to its nuanced effects on receptor dynamics. | ||||||
(±)-Nicotine | 22083-74-5 | sc-212379 sc-212379A sc-212379B sc-212379C | 250 mg 500 mg 5 g 10 g | $370.00 $735.00 $7140.00 $13770.00 | 1 | |
(+/-)-Nicotine is a well-known exogenous activator of nAChRs, including AChRαIt mimics the effects of acetylcholine and can lead to receptor activation. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $33.00 $37.00 $52.00 | 1 | |
Choline chloride is an essential nutrient that can activate nAChRs, including AChRαIt is a precursor for acetylcholine synthesis and can modulate receptor activity. | ||||||