Date published: 2025-11-26

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AChE Substrates

Santa Cruz Biotechnology now offers a broad range of AChE Substrates for use in various applications. AChE substrates are specialized compounds used to study acetylcholinesterase (AChE), an essential enzyme responsible for breaking down the neurotransmitter acetylcholine in the synaptic cleft. This process is crucial for terminating synaptic transmission and ensuring proper nervous system function. In scientific research, AChE substrates are fundamental tools for investigating the enzymatic activity of acetylcholinesterase, understanding its kinetic properties, and exploring its role in neural signaling pathways. Researchers utilize these substrates to measure AChE activity in various biological samples, including tissues, cell cultures, and purified enzyme preparations. By employing AChE substrates, scientists can gain insights into the regulation of neurotransmission, the impact of enzyme inhibitors, and the physiological and biochemical processes influenced by acetylcholine levels. High-purity AChE substrates provided by Santa Cruz Biotechnology ensure that experiments are conducted with precision and reproducibility, yielding reliable data that contribute to advancing knowledge in neurobiology and enzymology. These substrates are also essential in the development of assays for screening potential enzyme modulators and studying the effects of genetic or pharmacological manipulations on AChE activity. By offering a comprehensive selection of AChE substrates, Santa Cruz Biotechnology supports the scientific community in uncovering novel insights into cholinergic signaling and enzymatic regulation. View detailed information on our available AChE Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

S-Butyrylthiocholine Iodide

1866-16-6sc-286740
sc-286740A
sc-286740B
sc-286740C
5 g
50 g
100 g
500 g
$59.00
$587.00
$959.00
$3927.00
(0)

S-Butyrylthiocholine Iodide acts as a potent substrate for cholinesterases, exhibiting rapid hydrolysis due to its electrophilic carbonyl group. The presence of the thioether moiety enhances nucleophilic attack, facilitating swift enzymatic interactions. Its iodide component contributes to unique solubility characteristics, influencing reaction kinetics and stability in various environments. This compound's structural features promote specific binding affinities, impacting its reactivity in biochemical pathways.

Butyrylcholine chloride

2963-78-2sc-255007
sc-255007A
10 g
25 g
$54.00
$138.00
(0)

Butyrylcholine chloride is characterized by its reactive acyl chloride functionality, which readily engages in nucleophilic acyl substitution reactions. The chloride ion enhances its electrophilicity, making it a prime target for nucleophiles. This compound exhibits unique solubility properties in polar solvents, influencing its reactivity profile. Its ability to form stable intermediates during hydrolysis contributes to distinct reaction kinetics, allowing for selective interactions in various chemical environments.

Acetylthiocholine iodide

1866-15-5sc-208323
sc-208323A
sc-208323B
sc-208323C
sc-208323D
1 g
5 g
25 g
100 g
250 g
$36.00
$85.00
$362.00
$1153.00
$2657.00
(0)

Acetylthiocholine iodide features a thioester linkage that enhances its reactivity through the formation of thiol derivatives upon nucleophilic attack. The iodide moiety increases electrophilic character, facilitating rapid interactions with nucleophiles. This compound demonstrates unique solubility in organic solvents, which can influence its reactivity and stability. Its propensity to undergo hydrolysis leads to distinct reaction pathways, allowing for diverse chemical transformations.

Acetylthiocholine chloride

6050-81-3sc-257066
sc-257066A
1 g
5 g
$95.00
$356.00
(0)

Acetylthiocholine chloride exhibits a unique reactivity profile due to its quaternary ammonium structure, which enhances its interaction with nucleophiles. The chloride ion contributes to its electrophilic nature, promoting swift reaction kinetics. This compound is highly soluble in polar solvents, affecting its stability and reactivity. Its ability to form stable complexes with various ligands opens pathways for diverse synthetic applications, showcasing its versatility in chemical reactions.