The activators listed for Alpha-1 Antitrypsin (AAT) are considered for their potential indirect effects on AAT activity or expression. These compounds range from naturally occurring substances like EGCG and Curcumin. They operate through various mechanisms, influencing cellular signaling and metabolic pathways, which can create an environment conducive to the activity or expression of AAT.
Compounds like Forskolin and Sildenafil, affecting second messenger systems (cAMP and cGMP), play important roles in a wide array of cellular processes that might indirectly influence AAT. Similarly, Curcumin and Resveratrol, with their broad impact on cellular signaling, could potentially modulate the activity of AAT. Using these indirect activators is a strategic approach to influence proteins like AAT, especially when direct activators are not well-established. This method highlights the importance of understanding how broader cellular contexts and signaling networks can regulate protein functions. Each compound, by modulating specific pathways, can contribute to a cellular environment that may enhance the activity or expression of proteins like AAT, illustrating the complex nature of protein regulation and the interconnectedness of cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin increases cAMP levels, potentially influencing pathways that regulate AAT expression or activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, with its antioxidant properties, may impact oxidative stress pathways, indirectly affecting AAT. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to modulate several signaling pathways, resveratrol might indirectly affect AAT. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
By affecting GSK-3 signaling, lithium chloride could potentially influence AAT. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin, known to influence the AMPK pathway, may have indirect effects on AAT. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, rapamycin might indirectly affect AAT through the mTOR signaling pathway. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, impacting gene expression, could indirectly influence AAT. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin affects various signaling pathways, potentially impacting AAT. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Influencing NAD+ metabolism and related pathways, this form of vitamin B3 might impact AAT. | ||||||