Date published: 2025-12-18

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AAT-1 Activators

The activators listed for Alpha-1 Antitrypsin (AAT) are considered for their potential indirect effects on AAT activity or expression. These compounds range from naturally occurring substances like EGCG and Curcumin. They operate through various mechanisms, influencing cellular signaling and metabolic pathways, which can create an environment conducive to the activity or expression of AAT.

Compounds like Forskolin and Sildenafil, affecting second messenger systems (cAMP and cGMP), play important roles in a wide array of cellular processes that might indirectly influence AAT. Similarly, Curcumin and Resveratrol, with their broad impact on cellular signaling, could potentially modulate the activity of AAT. Using these indirect activators is a strategic approach to influence proteins like AAT, especially when direct activators are not well-established. This method highlights the importance of understanding how broader cellular contexts and signaling networks can regulate protein functions. Each compound, by modulating specific pathways, can contribute to a cellular environment that may enhance the activity or expression of proteins like AAT, illustrating the complex nature of protein regulation and the interconnectedness of cellular processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin increases cAMP levels, potentially influencing pathways that regulate AAT expression or activity.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG, with its antioxidant properties, may impact oxidative stress pathways, indirectly affecting AAT.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Known to modulate several signaling pathways, resveratrol might indirectly affect AAT.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

By affecting GSK-3 signaling, lithium chloride could potentially influence AAT.

Metformin

657-24-9sc-507370
10 mg
$77.00
2
(0)

Metformin, known to influence the AMPK pathway, may have indirect effects on AAT.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

As an mTOR inhibitor, rapamycin might indirectly affect AAT through the mTOR signaling pathway.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Sodium butyrate, impacting gene expression, could indirectly influence AAT.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$94.00
$173.00
$255.00
$423.00
26
(1)

Capsaicin affects various signaling pathways, potentially impacting AAT.

Nicotinamide riboside

1341-23-7sc-507345
10 mg
$411.00
(0)

Influencing NAD+ metabolism and related pathways, this form of vitamin B3 might impact AAT.