Date published: 2026-5-28

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HPA Inhibitors

Santa Cruz Biotechnology now offers a broad range of HPA Inhibitors for use in various applications. HPA Inhibitors are essential tools for studying the function and regulation of heparanase (HPA), an enzyme that plays a critical role in the degradation of heparan sulfate proteoglycans in the extracellular matrix. By specifically inhibiting heparanase activity, researchers can investigate the pathways and mechanisms through which this enzyme influences various cellular processes. In scientific research, HPA Inhibitors are used to explore the downstream effects of heparanase inhibition on cellular behavior and tissue remodeling. These inhibitors help explain the role of heparanase in modulating the extracellular matrix and provide insights into how the enzyme contributes to processes such as inflammation and cellular communication. Researchers employ HPA Inhibitors to study the molecular mechanisms by which heparanase mediates its effects and to identify potential targets for modulating its activity in research settings. Additionally, these inhibitors are valuable in high-throughput screening assays aimed at identifying new modulators of heparanase activity, aiding in the discovery of novel regulatory pathways and potential research targets. The use of HPA Inhibitors supports the development of experimental models to dissect the complex interactions between heparanase and other components of the extracellular matrix, enhancing our understanding of cellular regulation and adaptation. By enabling precise control over heparanase activity, these inhibitors facilitate detailed studies of the enzyme's role in cellular physiology. View detailed information on our available HPA Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$152.00
$214.00
$728.00
$2601.00
$10965.00
$21838.00
$41096.00
5
(1)

Suramin sodium is a complex polysulfonated naphthylurea that exhibits unique interactions with various biological macromolecules. Its extensive sulfonate groups facilitate strong electrostatic interactions, enhancing binding affinity to proteins and nucleic acids. This compound can disrupt specific signaling pathways by altering protein conformation and function. Its high molecular weight and hydrophilicity contribute to its distinct kinetic behavior, influencing diffusion rates and interaction dynamics in biological systems.