8-oxoG DNA Lesion Antibodies

Santa Cruz Biotechnology features a diverse variety of 8-oxoG DNA Lesion monoclonal antibodies for the detection and analysis of 8-oxo-7,8-dihydroguanine, a common oxidative DNA lesion. Applications include western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The 8-oxoG DNA lesion serves as a critical marker of oxidative stress and DNA damage, playing a significant role in the development of various diseases, including cancer. Mutations and genomic instability can occur due to 8-oxoG lesions, making their study essential for understanding cellular responses to oxidative stress and the mechanisms of disease progression. Researchers frequently monitor 8-oxoG levels to assess oxidative damage in cellular DNA and evaluate the effectiveness of antioxidant treatments. Understanding the formation and repair of 8-oxoG lesions provides valuable insights into aging processes and neurodegenerative disorders. Advanced detection methods using specific molecular tools allow scientists to track DNA damage events in real-time. The high-quality monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance their understanding of oxidative DNA damage and its role in human health and disease.