Date published: 2026-4-24

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60 kDa Ro/SSA Inhibitors

60 kDa Ro/SSA inhibitors belong to a specific chemical class of compounds designed to modulate the activity of the 60 kDa Ro/SSA protein, also known as SSA1 or Ro60. This protein is an autoantigen associated with certain autoimmune diseases, including systemic lupus erythematosus (SLE) and Sjögren's syndrome. Inhibitors of 60 kDa Ro/SSA are designed to selectively target this protein and interfere with its function, potentially impacting its role in cellular processes related to autoimmunity. The mechanism of action of these inhibitors typically involves direct interaction with the 60 kDa Ro/SSA protein or its associated binding partners, disrupting its normal function and cellular interactions. Researchers use 60 kDa Ro/SSA inhibitors to gain insights into the specific functions and molecular interactions involving this protein in different autoimmune-related contexts. Understanding the structural characteristics and mechanisms of 60 kDa Ro/SSA inhibitors is crucial for advancing knowledge in this area and may have broader implications for future research in autoimmune diseases and related fields.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Quinacrine, Dihydrochloride

69-05-6sc-204222
sc-204222B
sc-204222A
sc-204222C
sc-204222D
100 mg
1 g
5 g
200 g
300 g
$46.00
$57.00
$87.00
$3257.00
$4821.00
4
(2)

Quinacrine is a compound known for its inhibitory effects on 60 kDa Ro/SSA, affecting its function in certain cellular processes.

hydroxychloroquine

118-42-3sc-507426
5 g
$57.00
1
(0)

Hydroxychloroquine is an antimalarial drug that has been reported to inhibit 60 kDa Ro/SSA in certain experimental models.

Thalidomide

50-35-1sc-201445
sc-201445A
100 mg
500 mg
$111.00
$357.00
8
(0)

Thalidomide is an agent in research known for its multiple effects, and it has been studied as a potential inhibitor of 60 kDa Ro/SSA.

Auranofin

34031-32-8sc-202476
sc-202476A
sc-202476B
25 mg
100 mg
2 g
$153.00
$214.00
$4000.00
39
(2)

Auranofin is a gold-containing compound that has been reported to affect 60 kDa Ro/SSA function in certain cellular contexts.

Hydroquinidine

1435-55-8sc-250132
5 g
$68.00
(1)

Dihydroquinidine is a stereoisomer of quinidine and has been studied for its inhibitory effects on 60 kDa Ro/SSA.

Tilorone dihydrochloride

27591-69-1sc-237108
100 mg
$102.00
(1)

Trametinib is a small molecule inhibitor primarily known for its effects on MEK, but it has also been reported to inhibit 60 kDa Ro/SSA in certain cellular contexts.