4933425O20Rik Inhibitors
Tmem239 Inhibitors are compounds that can influence the activity of the Tmem239 protein by modulating various cellular processes and pathways that Tmem239 may be associated with. These inhibitors work by affecting the environment in which Tmem239 operates rather than binding directly to the protein. For instance, compounds such as Verapamil, Amiloride, and Ouabain can alter membrane ion gradients, which may impact the function of Tmem239 if it is involved in ion transport. Similarly, Genistein can disrupt phosphorylation-dependent signaling pathways; if Tmem239 is a component of such pathways, its function can be affected.
The chemical class encompasses a diverse range of mechanisms. Cholesterol, by modifying membrane fluidity, and GW4869, by affecting lipid composition, can change the microenvironment of Tmem239, potentially altering its activity. Propranolol and W-7 target specific signaling pathways, which can influence Tmem239 indirectly if it interacts with these pathways. Moreover, compounds like Brefeldin A and Dynasore disrupt intracellular trafficking and endocytosis, respectively, which can affect the localization and stability of Tmem239. Phloretin and Monensin, through their influence on nutrient transporters and ionophores, can create changes in cellular homeostasis that may affect Tmem239 indirectly.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
A calcium channel blocker that can inhibit calcium ion transport across cell membranes, potentially affecting Tmem239 if it is involved in calcium homeostasis. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor that can disrupt signal transduction pathways involving phosphorylation, possibly affecting Tmem239 if it participates in such pathways. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $56.00 | 6 | |
An inhibitor of certain ion channels and transporters, particularly Na+/H+ exchanger, which can influence ion balance and indirectly affect Tmem239 function if it is involved in ion transport. | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $26.00 $2754.00 $126.00 $206.00 $572.00 $86.00 | 11 | |
A major component of cell membranes that can alter membrane fluidity and potentially affect the function of membrane proteins such as Tmem239. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
A beta-blocker that can inhibit adrenergic signaling, potentially influencing Tmem239 if it interacts with adrenergic pathways. | ||||||
Phloretin | 60-82-2 | sc-3548 sc-3548A | 200 mg 1 g | $63.00 $250.00 | 13 | |
A dihydrochalcone that can inhibit glucose transporters, potentially affecting Tmem239 if it is associated with cellular nutrient uptake. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
An inhibitor of ADP-ribosylation factor (ARF), which can disrupt vesicle trafficking and potentially influence Tmem239 if it is involved in protein trafficking. | ||||||
GW4869 | 6823-69-4 | sc-218578 sc-218578A | 5 mg 25 mg | $199.00 $599.00 | 24 | |
An inhibitor of sphingomyelinase that can affect lipid raft composition and potentially Tmem239 if it localizes in such microdomains. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
A small molecule that inhibits dynamin-dependent endocytosis, potentially influencing Tmem239 if it undergoes endocytosis for regulation. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
An ionophore that can disrupt ion gradients, potentially affecting Tmem239 if it is involved in maintaining ion homeostasis. | ||||||