4930570C03Rik Activators
"4930570C03Rik Activators encompass a diverse group of chemical compounds that facilitate the enhancement of the protein's activity through distinct cellular signaling pathways. For instance, Forskolin, by raising cAMP levels, and Sildenafil, by maintaining cGMP levels, both augment intracellular cyclic nucleotide concentrations, which could activate protein kinase A or other cyclic nucleotide-dependent processes that phosphorylate and enhance the activity of 4930570C03Rik. "4930570C03Rik Activators encompass a diverse group of chemical compounds that facilitate the enhancement of the protein's activity through distinct cellular signaling pathways. For instance, Forskolin, by raising cAMP levels, and Sildenafil, by maintaining cGMP levels, both augment intracellular cyclic nucleotide concentrations, which could activate protein kinase A or other cyclic nucleotide-dependent processes that phosphorylate and enhance the activity of 4930570C03Rik.
Akt Activators encompass a diverse array of chemical compounds that orchestrate the amplification of Akt's kinase activity through various upstream signaling pathways. The binding of growth factors such as insulin and IGF-1 to their respective receptors initiates a cascade of phosphorylation events culminating in the activation of the PI3K/Akt pathway, directly enhancing Akt's role in promoting cell survival, growth, and metabolism. Similarly, EGF and PDGF engage their cognate receptors to activate PI3K, resulting in the phosphorylation and subsequent activation of Akt. In these scenarios, Akt serves as a critical node in transducing extracellular signals into intracellular actions that support key cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, which can activate calcium-dependent kinases and phosphatases that modulate the functional state of 4930570C03Rik through phosphorylation or dephosphorylation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Phorbol 12-myristate 13-acetate (PMA) activates protein kinase C (PKC), which then may phosphorylate 4930570C03Rik or its associated regulatory proteins, leading to increased activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is a specific inhibitor of MEK, which is involved in the MAPK/ERK pathway. If 4930570C03Rik is activated by ERK signaling, inhibiting upstream elements with PD 98059 could indirectly enhance its activity by altering feedback loops. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibits PI3K, altering the PI3K/AKT pathway. If 4930570C03Rik is modulated by AKT or related downstream signaling, this compound could indirectly increase its activity through pathway modulation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. If 4930570C03Rik is part of a signaling cascade regulated by p38 MAPK, inhibition with SB203580 could result in enhanced activity of 4930570C03Rik due to the removal of negative feedback loops. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is a calcium ionophore that raises intracellular calcium levels, potentially activating 4930570C03Rik if it is regulated by calcium-sensitive signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This compound is known to modulate various kinases and has antioxidant properties. If 4930570C03Rik activity is regulated by kinases that are targets of this compound, it could lead to enhanced activation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that could enhance the activity of 4930570C03Rik by inhibiting competitive signaling pathways or kinases that negatively regulate 4930570C03Rik. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin is a protein synthesis inhibitor that activates stress-activated protein kinases. If the activity of 4930570C03Rik is modulated by such stress pathways, anisomycin could lead to its enhanced activation. | ||||||