4930422I07Rik Activators
Chemical activators of zinc finger protein 949 include a variety of metal ions that interact with the zinc finger motifs integral to the protein's structure and function. Zinc, naturally essential for the maintenance of the zinc finger domain's configuration, can directly enhance the DNA-binding ability of zinc finger protein 949 when it binds to its motifs. Similarly, copper(II) sulfate and nickel(II) sulfate can substitute for zinc in these domains, which may result in a functional activation of the protein's DNA-binding capacity. Cobalt(II) chloride, by binding to the zinc finger domain, may lead to an alternative conformation that results in the activation of zinc finger protein 949's ability to engage with DNA sequences.
Additionally, cadmium chloride, lead(II) acetate, and mercury(II) chloride can interact with the zinc-binding sites of zinc finger protein 949, potentially leading to structural alterations that activate the protein's DNA-binding function. Silver nitrate can also bind to zinc finger motifs, activating zinc finger protein 949 by inducing favorable structural changes for DNA interaction. Arsenic trioxide binds to thiol groups within the protein, which can activate the DNA-binding function, while chromium(III) chloride can cause conformational changes that likewise activate the protein's interaction with DNA. Manganese(II) chloride and iron(II) sulfate can displace zinc, potentially leading to activation of zinc finger protein 949 by promoting structural changes that enhance its capability to bind to DNA, thus activating the protein's function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc can activate zinc finger protein 949 by directly binding to the zinc finger motifs, which are crucial for the structural integrity and function of the protein. This binding enhances the DNA-binding ability of zinc finger protein 949, leading to its functional activation. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Copper ions can bind to zinc finger domains, replacing zinc and changing the conformation of zinc finger protein 949. This conformational change can result in the functional activation of the protein's DNA-binding capacity. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
Cadmium can displace zinc in zinc finger motifs, potentially altering the structure of zinc finger protein 949 in a way that activates its binding to target DNA sequences. | ||||||
Nickel Sulfate | 7786-81-4 | sc-507407 | 5 g | $63.00 | ||
Nickel ions can interact with zinc finger proteins by binding to the zinc binding sites. For zinc finger protein 949, this can cause an activation of its DNA binding function through structural changes induced by nickel substitution for zinc. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
Cobalt can bind to the zinc finger domain, which may lead to an alternative folding or conformation that results in the activation of the DNA-binding function of zinc finger protein 949. | ||||||
Lead(II) Acetate | 301-04-2 | sc-507473 | 5 g | $83.00 | ||
Lead can interact with zinc-binding sites within the zinc finger protein 949, potentially altering its three-dimensional structure to activate the protein's ability to interact with DNA. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $112.00 $371.00 $1060.00 | 1 | |
Silver ions have the ability to bind to proteins with zinc finger motifs, which can cause an activation of zinc finger protein 949 by inducing structural changes that favor DNA interaction. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Arsenic can bind to thiol groups in proteins; in the case of zinc finger protein 949, this could lead to changes that activate its DNA-binding function. | ||||||
Chromium(III) chloride | 10025-73-7 | sc-239548 sc-239548A sc-239548B | 25 g 100 g 1 kg | $68.00 $272.00 $2462.00 | ||
Chromium can affect the structure of zinc finger domains; for zinc finger protein 949, chromium binding could alter its configuration in a manner that activates its interaction with DNA. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese ions can bind to the zinc finger motifs and potentially activate zinc finger protein 949 by promoting structural changes conducive to DNA binding. | ||||||