4921510H08Rik Inhibitors
Chemicals classified as indirect CCER1 inhibitors primarily act by altering the cellular pathways that can influence the expression, stability, or function of CCER1. These chemicals have diverse mechanisms of action. For instance, Cycloheximide and Rapamycin can inhibit protein synthesis, which can lead to a reduction in CCER1 levels. Similarly, DNA or RNA synthesis inhibitors like Mitomycin C and Actinomycin D can decrease the transcription of genes, potentially reducing CCER1 synthesis.
Paclitaxel and Nocodazole affect the microtubule dynamics, which are critical for cell cycle progression and mitosis, potentially impacting the cellular levels of CCER1 due to changes in cell cycle dynamics. Cell cycle inhibitors such as Roscovitine can disrupt the cycle at specific checkpoints, indirectly affecting the expression of CCER1 which may be regulated during cell division.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis, potentially reducing CCER1 expression by preventing its translation. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
DNA crosslinking agent that can lead to reduced transcription of various genes, possibly including CCER1. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Inhibits RNA polymerase, potentially decreasing CCER1 mRNA synthesis. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules and can disrupt cell division, possibly affecting CCER1 levels due to altered cell cycle dynamics. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Microtubule destabilizing agent, potentially altering cell cycle progression and CCER1 regulation. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
CDK inhibitor, potentially affecting cell cycle progression and thus the regulation of CCER1 expression. | ||||||
PI-103 | 371935-74-9 | sc-203193 sc-203193A | 1 mg 5 mg | $32.00 $128.00 | 3 | |
Inhibits PI3K/Akt/mTOR pathway, which can regulate protein synthesis and potentially influence CCER1 levels. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK signaling, potentially altering transcription factors that regulate CCER1 expression. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Inhibits MEK1/2, potentially affecting MAPK/ERK pathway and CCER1 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, potentially affecting pathways that regulate CCER1 expression or stability. | ||||||