2310004I24Rik Activators
2310004I24Rik Activators encompass a diverse array of chemical compounds that indirectly augment the functional activity of 2310004I24Rik through various cellular signaling mechanisms. Compounds such as Forskolin and Isoproterenol increase intracellular cAMP, which in turn activates PKA; this kinase phosphorylates numerous substrates that might include elements associated with 2310004I24Rik signaling, thereby enhancing its activity. Oleic Acid, by altering membrane fluidity, facilitates the interaction of 2310004I24Rik with other signaling molecules, thereby enhancing its activity. Similarly, Sphingosine-1-phosphate, through G protein-coupled receptor signaling, and Curcumin, with its broad effects on cell signaling pathways, could potentiate the action of kinases and other proteins that are part of the 2310004I24Rik network. Lithium Chloride and Retinoic Acid modify the signaling milieu by inhibiting GSK-3 and altering gene expression patterns, respectively, which can result in an enhanced functional state of 2310004I24Rik.
The functional activity of 2310004I24Rik is further influenced by compounds that modulate intracellular calcium and lipid signaling. Ionomycin and A23187, as calcium ionophores, increase intracellular calcium levels, activating calcium-dependent kinases and phosphatases that may interact with or modify the activity of 2310004I24Rik. Phorbol 12-myristate 13-acetate acts as a PKC activator, a kinase with numerous substrates that could intersect with 2310004I24Rik pathways, enhancing its functional status. Additionally, 8-Bromo-cAMP, a cAMP analog, and 17β-Estradiol, through estrogen receptor-mediated signaling, also contribute to the array of mechanisms leading to the activation of 2310004I24Rik. Collectively, these activators work through distinct but interconnected biochemical pathways to potentiate the functional activity of 2310004I24Rik without requiring upregulation of its expression or direct activation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC), which can phosphorylate and activate various substrates involved in the signaling cascades that include 2310004I24Rik, thereby enhancing its activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that raises intracellular calcium levels. Elevated calcium can trigger signaling events involving calmodulin and calcium/calmodulin-dependent protein kinases, which may result in the activation of 2310004I24Rik through calcium-dependent signaling pathways. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
8-Bromo-cAMP is a cell-permeable cAMP analog that activates cAMP-dependent pathways. This compound can enhance the activity of 2310004I24Rik by mimicking the action of endogenous cAMP and activating PKA, which in turn could phosphorylate and activate 2310004I24Rik or its associated proteins. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Oleic Acid is a monounsaturated fatty acid that can modulate membrane fluidity and influence membrane-associated signaling pathways. This alteration in membrane dynamics can enhance the activation of 2310004I24Rik by affecting the protein's interaction with other signaling molecules within the membrane. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is a calcium ionophore that increases intracellular calcium levels, similar to ionomycin. This elevation in calcium can activate signaling pathways that lead to the activation of 2310004I24Rik, as calcium-dependent proteins and kinases modulate the protein's activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate is a bioactive lipid that acts through G protein-coupled receptors to initiate signaling cascades. It can indirectly enhance the activity of 2310004I24Rik by modulating intracellular signaling pathways, which could include kinase activation that is relevant to the protein's function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid, a metabolite of vitamin A, acts on nuclear receptors and can influence gene expression patterns. By altering the transcription of downstream genes, retinoic acid can enhance the activity of 2310004I24Rik by affecting the cellular environment in which the protein operates. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride inhibits glycogen synthase kinase 3 (GSK-3). By inhibiting GSK-3, it can lead to the activation of signaling pathways that may indirectly enhance the functionality of 2310004I24Rik by affecting proteins and substrates within the same signaling networks. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
17β-Estradiol binds to estrogen receptors and can modulate various signaling pathways. Through these pathways, the activity of 2310004I24Rik may be enhanced by the downstream effects of estrogen receptor activation, which can include the modification of signaling proteins that interact with 2310004I24Rik. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has multiple cellular targets and can modulate various signaling pathways. By affecting these pathways, curcumin can indirectly enhance the activity of 2310004I24Rik through its influence on cell signaling molecules and kinases that may be part of the protein's signaling network. | ||||||