Date published: 2026-4-24

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17beta-HSD Inhibitors

Santa Cruz Biotechnology now offers a broad range of 17beta-HSD Inhibitors for use in various applications. 17beta-HSD inhibitors are specialized compounds that target the enzyme 17β-hydroxysteroid dehydrogenase, which plays a crucial role in the metabolism of sex steroids by converting less active forms of hormones such as estrone and androstenedione into their more active counterparts, estradiol and testosterone. These inhibitors are important tools in scientific research for studying the regulation of steroid hormone activity at the tissue level and understanding their broader impact on biological processes such as development, reproduction, and metabolic regulation. Researchers utilize 17beta-HSD inhibitors to investigate the enzyme's role in the modulation of steroid hormone levels within different tissues, and how this regulation affects various physiological functions. These inhibitors are particularly valuable in studies exploring the mechanisms of hormone-dependent diseases, the development of hormone-responsive tissues, and the intricate balance of hormone synthesis and degradation. By providing high-purity 17beta-HSD inhibitors, Santa Cruz Biotechnology ensures that experiments are conducted with high precision and reproducibility, yielding reliable data crucial for advancing scientific knowledge. The availability of these inhibitors supports researchers in their efforts to dissect complex endocrine pathways, develop new experimental models, and uncover novel insights into steroid hormone regulation. View detailed information on our available 17beta-HSD Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Coumestrol

479-13-0sc-205638
sc-205638A
10 mg
25 mg
$207.00
$321.00
2
(1)

Coumestrol acts as a selective modulator of 17β-hydroxysteroid dehydrogenase, exhibiting unique binding affinities that influence steroid metabolism. Its molecular structure allows for specific interactions with the enzyme's active site, enhancing substrate specificity and altering reaction kinetics. This compound can shift the equilibrium of steroid interconversion, impacting hormonal balance and metabolic pathways. Its distinct conformational dynamics contribute to the regulation of various physiological processes.