1700018C11Rik Activators
1700018C11Rik Activators are a diverse set of chemical compounds that interact with various signaling pathways to indirectly enhance the functional activity of 1700018C11Rik. Compounds such as Forskolin and 8-Br-cAMP elevate intracellular cAMP levels, which can activate PKA and subsequently lead to phosphorylation events enhancing the activity of 1700018C11Rik. 1700018C11Rik Activators are a collection of chemical compounds that indirectly influence the functional activity of the protein 1700018C11Rik through modulation of various cellular pathways.1700018C11Rik Activators are a collection of chemical compounds that indirectly influence the functional activity of the protein 1700018C11Rik through modulation of various cellular pathways. Forskolin and IBMX play roles in the elevation of intracellular cAMP, with Forskolin directly activating adenylate cyclase and IBMX inhibiting the degradation of cAMP, leading to a sustained activation of protein kinase A (PKA). PKA, being a kinase that can target a multitude of proteins, might phosphorylate 1700018C11Rik assuming it has a phosphorylation site, thereby potentially enhancing its functional activity.
Epigallocatechin gallate, known for its kinase modulation properties, could also influence the activity of 1700018C11Rik by affecting its phosphorylation status. Ionomycin and A23187, both acting as calcium ionophores, can increase the intracellular calcium concentration, which might activate calcium-dependent kinases or phosphatases that target 1700018C11Rik, assuming its activity is regulated by calcium signaling. Furthermore, the activation of protein kinase C (PKC) by PMA might lead to the phosphorylation of 1700018C11Rik if it is within the scope of PKC's substrate specificities. Spermine, through its capacity to stabilize DNA and modulate ion channels, could influence the function of 1700018C11Rik if its activity is affected by such cellular conditions. Nicotinamide riboside, as a precursor to NAD+, could impact 1700018C11Rik's activity by altering ADP-ribosylation patterns or redox states that 1700018C11Rik is sensitive to.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
8-Br-cAMP, a cAMP analog, directly stimulates cAMP-dependent pathways which could activate PKA, potentially leading to phosphorylation events that enhance the activity of 1700018C11Rik through cAMP-responsive elements. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially modulating calcium-dependent protein kinases and phosphatases that might interact with or modify 1700018C11Rik to increase its activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which could phosphorylate substrates or change cellular localization of proteins that indirectly enhance the functional activity of 1700018C11Rik. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX is a non-specific inhibitor of phosphodiesterases, leading to an increase in intracellular cAMP levels, which may indirectly upregulate PKA activity and subsequent phosphorylation that could enhance the activity of 1700018C11Rik. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is an inhibitor of PI3K, which may shift the signaling balance towards pathways that indirectly activate 1700018C11Rik by reducing competitive signaling through the PI3K/Akt pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK, which could alter the phosphorylation state of proteins within the MAPK pathway, potentially leading to enhanced activation of 1700018C11Rik. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that may reduce competitive signaling through these kinases, possibly enhancing signaling pathways that positively influence the activity of 1700018C11Rik. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a known inhibitor of several protein kinases and could indirectly enhance the activity of 1700018C11Rik by altering the phosphorylation state of proteins important for 1700018C11Rik's functional pathway. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate is a bioactive lipid that can activate G-protein coupled receptors and downstream signaling pathways, potentially leading to indirect activation of 1700018C11Rik through lipid signaling pathways. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that leads to increased intracellular calcium levels, potentially activating calcium-dependent signaling pathways that indirectly increase the activity of 1700018C11Rik. | ||||||