Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
UBE2S Antibody (C-1) is a high quality monoclonal UBE2S antibody (also designated UBE2S antibody) suitable for the detection of the UBE2S protein of mouse, rat and human origin. UBE2S Antibody (C-1) is available as both the non-conjugated anti-UBE2S antibody form, as well as multiple conjugated forms of anti-UBE2S antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBE2S (ubiquitin-conjugating enzyme E2S), also known as EPF5 or E2EPF, is a 222 amino acid protein that belongs to the E2 family of ubiquitin-conjugating enzymes. Involved in the protein degradation pathway, UBE2S catalyzes the ATP-dependent attachment of ubiquitin (Ub) to target proteins, thereby tagging them for subsequent destruction by the proteasome. UBE2S is thought to increase the rate of tumor cell proliferation, invasion and metastasis through the VHL (von Hippel-Lindau) pathway, suggesting a role for UBE2S in carcinogenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Can UBE2S (C-1): sc-390917 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Dr Ninau Qelp
Thank you for your question. Yes, UBE2S (C-1): sc-390917 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 5 out of
Great Antibody for Western blotWorked well at a 1:200 dilution for a western blot using whole cell lysate from breast cancer cell lines.
Date published: 2017-11-17
Rated 5 out of
Produced exceptional immunoperoxidase nuclearProduced exceptional immunoperoxidase nuclear and cytoplasmic staining in formalin fixed, paraffin-embedded human testis tissue. -SCBT QC
Date published: 2015-01-05
Rated 5 out of
Nice Western Blot data of UBE2S expression in Y79Nice Western Blot data of UBE2S expression in Y79, HeLa, MCF7 and PC-3 whole cell lysates. -SCBT QC