Molecular structure of Tylosin phosphate, CAS Number: 1405-53-4
Tylosin phosphate (CAS 1405-53-4)
Alternate Names:
Farmazin TB
Application:
Tylosin phosphate is an antibacterial agent employed against mycoplasma organisms
CAS Number:
1405-53-4
Molecular Weight:
1014.10
Molecular Formula:
C46H77NO17•H3PO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tylosin phosphate is a derivative of tylosin, a macrolide antibiotic produced by the bacterium Streptomyces fradiae. It consists of the tylosin molecule esterified with phosphate, enhancing its solubility in water, which is particularly beneficial for its formulation as a veterinary medicine. Tylosin phosphate functions by binding to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis. This action effectively halts bacterial growth, helping to control and eliminate infectious organisms. Tylosin phosphate is particularly effective against certain Gram-positive bacteria and a few Gram-negative bacteria, as well as being active against certain mycoplasmas.
Tylosin phosphate (CAS 1405-53-4) References
- Efficacy of in-feed tylosin phosphate for the treatment of necrotic enteritis in broiler chickens. | Brennan, J., et al. 2001. Poult Sci. 80: 1451-4. PMID: 11599704
- Growth performance of pigs fed diets with and without tylosin phosphate supplementation and reared in a biosecure all-in all-out housing system. | Van Lunen, TA. 2003. Can Vet J. 44: 571-6. PMID: 12892287
- Tylosin, a new antibiotic. II. Isolation, properties, and preparation of desmycosin, a microbiologically active degradation product. | HAMILL, RL., et al. 1961. Antibiot Chemother (Northfield). 11: 328-34. PMID: 13711004
- Effects of tylosin on bacterial mucolysis, Clostridium perfringens colonization, and intestinal barrier function in a chick model of necrotic enteritis. | Collier, CT., et al. 2003. Antimicrob Agents Chemother. 47: 3311-7. PMID: 14506046
- Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. | Pilcher, CM., et al. 2013. J Anim Sci. 91: 5687-95. PMID: 24126274
- Effect of in-feed administration and withdrawal of tylosin phosphate on antibiotic resistance in enterococci isolated from feedlot steers. | Beukers, AG., et al. 2015. Front Microbiol. 6: 483. PMID: 26074889
- Effects of intermittent feeding of tylosin phosphate during the finishing period on feedlot performance, carcass characteristics, antimicrobial resistance, and incidence and severity of liver abscesses in steers. | Müller, HC., et al. 2018. J Anim Sci. 96: 2877-2885. PMID: 29718254
- Consistency evaluation between matrix components ratio and microbiological potency of tylosin major components. | Hamidian, K., et al. 2018. Daru. 26: 155-164. PMID: 30361888
- In-Feed Tylosin Phosphate Administration to Feedlot Cattle Minimally Affects Antimicrobial Resistance. | Schmidt, JW., et al. 2020. J Food Prot. 83: 350-364. PMID: 31971461
- Investigation of a Reduction in Tylosin on the Prevalence of Liver Abscesses and Antimicrobial Resistance in Enterococci in Feedlot Cattle. | Davedow, T., et al. 2020. Front Vet Sci. 7: 90. PMID: 32185186
- Evaluation of immunoglobulin-Y in place of tylosin phosphate in the diets fed to Holstein Steers and preliminary analysis of liver abscess duration on animal growth performance. | Stotz, MK., et al. 2021. Transl Anim Sci. 5: txaa225. PMID: 33501416
- In vivo analysis the effect of antibiotic growth promoters (AGPs), Oxytetracycline di-hydrate and Tylosin phosphate on the intestinal microflora in broiler chicken. | Shah, SH., et al. 2022. Braz J Biol. 84: e258114. PMID: 35649037
- Tylosin phosphate (TP) and tylosin urea adduct (TUA) for the prevention of liver abscesses, improved weight gains and feed efficiency in feedlot cattle. | Brown, H., et al. 1973. J Anim Sci. 37: 1085-91. PMID: 4758014
- Oral administration of tylosin phosphate for treatment and prevention of proliferative enteropathy in pigs. | McOrist, S., et al. 1997. Am J Vet Res. 58: 136-9. PMID: 9028475
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tylosin phosphate, 1 g | sc-204932 | 1 g | $52.00 | |||
Tylosin phosphate, 5 g | sc-204932A | 5 g | $142.00 |